Publication Beamlines Strategic Pillar
Grebien, Florian; Vedadi, Masoud; Getlik, Matthäus; Giambruno, Roberto; Grover, Amit et al. (2015). Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. Nature Chemical Biology 11(8) , 571-578. 10.1038/nchembio.1859. [PDB: 4ql1] CMCF-ID Health
Grandin, Mélodie; Meier, Markus; Delcros, Jean Guy; Nikodemus, Denise; Reuten, Raphael et al. (2016). Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers. Cancer Cell 29(2) , 173-185. 10.1016/j.ccell.2016.01.001. [PDB: 4ove] CMCF-BM Health
Gould, Alister D.; Shilton, Brian H. (2010). Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate. Journal of Biological Chemistry 285(15) , 11290-11296. 10.1074/jbc.m109.089078. [PDB: 3hpi, 3kjt] CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Heinz, Leonhard X.; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. Journal of Biological Chemistry 291(46) , 24054-24064. 10.1074/jbc.m116.755801. CMCF-ID Health
Gonzalez-Lopez de Turiso, Felix; Sun, Daqing; Rew, Yosup; Bartberger, Michael D.; Beck, Hilary P. et al. (2013). Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors. Journal of Medicinal Chemistry 56(10) , 4053-4070. 10.1021/jm400293z. [PDB: 4jwr] CMCF-ID Health
Gomery, Kathryn; Müller-Loennies, Sven; Brooks, Cory L.; Brade, Lore; Kosma, Paul et al. (2012). Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proceedings of the National Academy of Sciences of the United States of America 109(51) , 20877-20882. 10.1073/pnas.1209253109. [PDB: 3v0w] CMCF-ID Health
Gobeil, Sophie M.C.; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M. et al. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins. Chemistry & Biology 21(10) , 1330-1340. 10.1016/j.chembiol.2014.07.016. [PDB: 4id4] CMCF-ID Health
Ghosh, Kaushik; Mazumder Tagore, Debarati; Anumula, Rushith; Lakshmaiah, Basanth; Kumar, P.P.B.S. et al. (2013). Crystal structure of rat intestinal alkaline phosphatase – Role of crown domain in mammalian alkaline phosphatases. Journal of Structural Biology 184(2) , 182-192. 10.1016/j.jsb.2013.09.017. [PDB: 4kjg] CMCF-ID Health
Getlik, Matthäus; Smil, David; Zepeda-Velázquez, Carlos; Bolshan, Yuri; Poda, Gennady et al. (2016). Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1). Journal of Medicinal Chemistry 59(6) , 2478-2496. 10.1021/acs.jmedchem.5b01630. [PDB: 5eam, 5eap] CMCF-ID Health
Gayda, Susan; Longenecker, Kenton L.; Judge, Russell A.; Swift, Kerry M.; Manoj, Sharmila et al. (2016). Three-dimensional structure, binding, and spectroscopic characteristics of the monoclonal antibody 43.1 directed to the carboxyphenyl moiety of fluorescein. Biopolymers 105(4) , 234-243. 10.1002/bip.22801. [PDB: 5dyo] CMCF-ID Health
Frank, Filipp; Hauver, Jesse; Sonenberg, Nahum; Nagar, Bhushan (2012). ArabidopsisArgonaute MID domains use their nucleotide specificity loop to sort small RNAs. EMBO Journal 31(17) , 3588-3595. 10.1038/emboj.2012.204. [PDB: 4g0x] CMCF-BM Health
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] CMCF-BM, CMCF-ID Health
Fowler, Melissa L.; McPhail, Jacob A.; Jenkins, Meredith L.; Masson, Glenn R.; Rutaganira, Florentine U. et al. (2016). Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11. Protein Science 25(4) , 826-839. 10.1002/pro.2879. [PDB: 5c46, 5c4g] CMCF-ID Health