Sanhueza, Carlos A.; Cartmell, Jonathan; El-Hawiet, Amr; Szpacenko, Adam; Kitova, Elena N. et al. (2015). Evaluation of a focused virtual library of heterobifunctional ligands for Clostridium difficile toxins. Organic and Biomolecular Chemistry 13(1) , 283-298. 10.1039/c4ob01838a. |
CMCF-BM |
Peer-Reviewed Article |
Health |
Badea, Ildiko; Poorghorban, Masoomeh; Das, Umashankar; Alaidi, Osama; Chitanda, Jackson et al. (2015). Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity. International Journal of Nanomedicine , 503-515. 10.2147/ijn.s70828. |
CMCF-BM, MID-IR |
Peer-Reviewed Article |
Health |
Loewen, Peter C.; Villanueva, Jacylyn; Switala, Jacek; Donald, Lynda J.; Ivancich, Anabella et al. (2015). Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity ofBacillus pumiluscatalase monitored by X-ray crystallography and EPR spectroscopy. Proteins: Structure. Function and Bioinformatics 83(5) , 853-866. 10.1002/prot.24777. [PDB: 4qol, 4qom, 4qon, 4qoo, 4qop, 4qoq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
King, Dustin T.; King, Andrew M.; Lal, Sarah M.; Wright, Gerard D.; Strynadka, Natalie C. J. et al. (2015). Molecular Mechanism of Avibactam-Mediated β-Lactamase Inhibition. ACS Infectious Diseases 1(4) , 175-184. 10.1021/acsinfecdis.5b00007. [PDB: 4s2i, 4s2j, 4s2k, 4s2n, 4s2o, 4s2p] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. [PDB: 4c1r, 4c1s] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Yachnin, Brahm J.; McEvoy, Michelle B.; MacCuish, Roderick J. D.; Morley, Krista L.; Lau, Peter C. K. et al. (2014). Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis. ACS Chemical Biology 9(12) , 2843-2851. 10.1021/cb500442e. [PDB: 4rg3] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Gobeil, Sophie M.C.; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M. et al. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins. Chemistry & Biology 21(10) , 1330-1340. 10.1016/j.chembiol.2014.07.016. [PDB: 4id4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Luan, Xiaojie; Campanucci, Verónica A.; Nair, Manoj; Yilmaz, Orhan; Belev, George et al. (2014). Pseudomonas aeruginosa
triggers CFTR-mediated airway surface liquid secretion in swine trachea. Proceedings of the National Academy of Sciences of the United States of America 111(35) , 12930-12935. 10.1073/pnas.1406414111. |
BMIT-BM |
Peer-Reviewed Article |
Health |
Anzar, Muhammad; Grochulski, Pawel; Bonnet, Brennan (2014). Synchrotron X-Ray Diffraction to Detect Glass or Ice Formation in the Vitrified Bovine Cumulus-Oocyte Complexes and Morulae. PLoS ONE 9(12) , e114801. 10.1371/journal.pone.0114801. |
CMCF-BM |
Peer-Reviewed Article |
Health |
Leung, Kevin K. K.; Shilton, Brian H. (2014). Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT. Biochemistry 54(1) , 47-59. 10.1021/bi500959t. [PDB: 4u7h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka et al. (2015). Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3. Nuclear Instruments and Methods in Physics Research. Section A: Accelerators. Spectrometers. Detectors and Associated Equipment 775, 1-4. 10.1016/j.nima.2014.11.088. |
BMIT-BM, BMIT-ID |
Peer-Reviewed Article |
Health |
Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. [PDB: 4ly8, 4m19, 4mlj, 4mlr, 4r53] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
René, Olivier; Fauber, Benjamin P.; Boenig, Gladys de Leon; Burton, Brenda; Eidenschenk, Céline et al. (2014). Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action. ACS Medicinal Chemistry Letters 6(3) , 276-281. 10.1021/ml500420y. [PDB: 4wqp] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
van Straaten, Karin E.; Kuttiyatveetil, Jijin R. A.; Sevrain, Charlotte M.; Villaume, Sydney A.; Jiménez-Barbero, Jesús et al. (2015). Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues. Journal of the American Chemical Society 137(3) , 1230-1244. 10.1021/ja511204p. [PDB: 4rpg, 4rph, 4rpj, 4rpk, 4rpl] |
CMCF-ID |
Peer-Reviewed Article |
Health |