| Lewis, Melissa; Meza-Avina, Maria Elena; Wei, Lianhu; Crandall, Ian E.; Bello, Angelica Mara et al. (2011). Novel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate Decarboxylase. Journal of Medicinal Chemistry 54(8) , 2891-2901. 10.1021/jm101642g. [PDB: 3mo7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sarhan, Maen F.; Tung, Ching-Chieh; Van Petegem, Filip; Ahern, Christopher A. (2012). Crystallographic basis for calcium regulation of sodium channels. Proceedings of the National Academy of Sciences of the United States of America 109(9) , 3558-3563. 10.1073/pnas.1114748109. [PDB: 4djc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Nicklisch, Sascha C. T.; Rees, Steven D.; McGrath, Aaron P.; Gökirmak, Tufan; Bonito, Lindsay T. et al. (2016). Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances 2(4) , e1600001-e1600001. 10.1126/sciadv.1600001. [PDB: 4xwk] |
CMCF-ID |
Peer-Reviewed Article |
Environment |
| Wahba, Haytham M.; Lecoq, Lauriane; Stevenson, Michael; Mansour, Ahmed; Cappadocia, Laurent et al. (2016). Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg–Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry 55(7) , 1070-1081. 10.1021/acs.biochem.5b01298. [PDB: 5c17] |
CMCF-ID |
Peer-Reviewed Article |
Environment |
| Marchetti, Adrian; Parker, Micaela S.; Moccia, Lauren P.; Lin, Ellen O.; Arrieta, Angele L. et al. (2008). Ferritin is used for iron storage in bloom-forming marine pennate diatoms. Nature 457(7228) , 467-470. 10.1038/nature07539. |
CMCF-ID |
Peer-Reviewed Article |
Environment |
| Pluvinage, Benjamin; Hehemann, Jan-Hendrik; Boraston, Alisdair B. (2013). Substrate Recognition and Hydrolysis by a Family 50 exo-β-Agarase, Aga50D, from the Marine Bacterium Saccharophagus degradans. Journal of Biological Chemistry 288(39) , 28078-28088. 10.1074/jbc.m113.491068. [PDB: 4bq4, 4bq5] |
CMCF-ID |
Peer-Reviewed Article |
Environment |
| Thede, Gina L. (2012). Biochemical and structural characterization of CpxP and CpxA, key components of an envelope stress response in Escherichia coli. Supervisor: Young, Howard; Glover, Mark. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R31C7M. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Leung, Charles (2011). Molecular basis of TopBP1 BRCT domain interactions in the DNA damage response. Supervisor: Glover, Mark. AB, Canada: University of Alberta. https://doi.org/10.7939/R3Q42H. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Blackler, Ryan J. (2016). Structural investigations into conformational diversity, polyspecificity, and binding mechanisms of near-germline antibodies. Supervisor: Evans, Stephen. BC, Canada: University of Victoria. http://hdl.handle.net/1828/7305. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Wu; Tao (2012). Structural and Functional Studies of the Core Splicing Factor Prp8. Supervisor: MacMillan, Andrew. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R3JD4Q10M. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Szewczyk; Paul Ralph (2014). Structural Studies of Multidrug Transporter Proteins. Supervisor: Saier, Milton. California, USA: University of California, San Diego. https://escholarship.org/uc/item/4sv4k03r. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Li; Zhijie (2015). Structural and Biochemical Characterization of the Mammalian Glycosyltransferases, N-acetylglucosaminyltransferase II and Protein O-fucosyltransferase 1. Supervisor: Rini, James M.. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/76678. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Basu; Koli (2016). Discovery and characterization of an antifreeze protein from Lake Ontario midges. Supervisor: Davies, Peter. Ontario, Canada: Queen's University. http://hdl.handle.net/1974/14360. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Aydin; Halil (2016). Structural and functional insights into the molecular mechanisms of viral-cell and cell-cell fusion. Supervisor: Lee, Jeffrey E.. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/80388. |
CMCF-ID |
Doctoral Thesis |
Agriculture |