| Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-G. Protein Data Bank: 3ki2. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-L. Protein Data Bank: 3ki6. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-I. Protein Data Bank: 3ki7. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-P. Protein Data Bank: 3ki4. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-M. Protein Data Bank: 3ki5. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-H. Protein Data Bank: 3ki3. |
CMCF-ID |
PDB Deposition |
Health |
| Jorgensen, R.; Edwards, P.R.; Merrill, A.R. (2010). Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-F. Protein Data Bank: 3ki1. |
CMCF-ID |
PDB Deposition |
Health |
| Jørgensen, René; Wang, Yolanda; Visschedyk, Danielle; Merrill, A Rod (2008). The nature and character of the transition state for the ADP‐ribosyltransferase reaction. EMBO Reports 9(8) , 802-809. 10.1038/embor.2008.90. [PDB: 2zit] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Jorgensen, R.; Merrill, A.R. (2008). Structure of the eEF2-ExoA-NAD+ complex. Protein Data Bank: 2zit. |
CMCF-ID |
PDB Deposition |
Health |
| Juang, Yu-Chi; Landry, Marie-Claude; Sanches, Mario; Vittal, Vinayak; Leung, Charles C.Y. et al. (2012). OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Molecular Cell 45(3) , 384-397. 10.1016/j.molcel.2012.01.011. [PDB: 4ddg] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Julien, Jean-Philippe; Cupo, Albert; Sok, Devin; Stanfield, Robyn L.; Lyumkis, Dmitry et al. (2013). Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer. Science 342(6165) , 1477-1483. 10.1126/science.1245625. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Kalynych, Sergei (2013). Structural and Functional Characterization of Polysaccharide Co-Polymerases. Supervisor: Nagar, Bhushan; Cygler, Mirek. Quebec, Canada: McGill University. http://digitool.Library.McGill.CA:80/R/-?func=dbin-jump-full&object_id=123183&silo_library=GEN01. |
CMCF-ID |
Doctoral Thesis |
Health |
| Kalynych, Sergei; Cherney, Maia; Bostina, Mihnea; Rouiller, Isabelle; Cygler, Miroslaw et al. (2014). Quaternary structure of WzzB and WzzE polysaccharide copolymerases. Protein Science 24(1) , 58-69. 10.1002/pro.2586. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kalynych, Sergei; Yao, Deqiang; Magee, James; Cygler, Miroslaw (2012). Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators. Journal of Biological Chemistry 287(19) , 15696-15705. 10.1074/jbc.m112.354837. [PDB: 4e2c, 4e2h, 4e2l] |
CMCF-ID |
Peer-Reviewed Article |
Health |