Publication Beamlines Strategic Pillar
Jørgensen, René; Wang, Yolanda; Visschedyk, Danielle; Merrill, A Rod (2008). The nature and character of the transition state for the ADP‐ribosyltransferase reaction. EMBO Reports 9(8) , 802-809. 10.1038/embor.2008.90. [PDB: 2zit] CMCF-ID Health
Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] CMCF-ID Health
Johal, A. R.; Blackler, R. J.; Alfaro, J. A.; Schuman, B.; Borisova, S. et al. (2013). pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology 24(3) , 237-246. 10.1093/glycob/cwt098. [PDB: 4fre, 4frh, 4frl, 4frm, 4fro, 4frp, 4frq] CMCF-ID Health
Jha, Vikash; Louis, Sherif; Chelikani, Prashen; Carpena, Xavi; Donald, Lynda J. et al. (2011). Modulation of Heme Orientation and Binding by a Single Residue in Catalase HPII of Escherichia coli. Biochemistry 50(12) , 2101-2110. 10.1021/bi200027v. [PDB: 3p9p, 3p9q, 3p9r, 3p9s, 3pq2, 3pq3, 3pq4, 3pq5, 3pq6, 3pq7, 3pq8] CMCF-ID Health
Jha, Vikash; Donald, Lynda J.; Loewen, Peter C. (2012). Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage. Archives of Biochemistry and Biophysics 525(2) , 207-214. 10.1016/j.abb.2011.11.022. [PDB: 3ttt, 3ttv, 3ttw, 3ttx] CMCF-ID Health
Jha, Vikash; Chelikani, Prashen; Carpena, Xavi; Fita, Ignacio; Loewen, Peter C. et al. (2012). Influence of main channel structure on H2O2 access to the heme cavity of catalase KatE of Escherichia coli. Archives of Biochemistry and Biophysics 526(1) , 54-59. 10.1016/j.abb.2012.06.010. [PDB: 4enp, 4enr, 4ens, 4ent, 4enu, 4env, 4enw] CMCF-ID Health
Jarvis, Thale C.; Davies, Douglas R.; Hisaminato, Akihiko; Resnicow, Daniel I.; Gupta, Shashi et al. (2015). Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure 23(7) , 1293-1304. 10.1016/j.str.2015.03.027. [PDB: 4zbn] CMCF-ID Health
James, Terrence W.; Frias-Staheli, Natalia; Bacik, John-Paul; Levingston Macleod, Jesica M.; Khajehpour, Mazdak et al. (2011). Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease. Proceedings of the National Academy of Sciences of the United States of America 108(6) , 2222-2227. 10.1073/pnas.1013388108. [PDB: 3pse, 3pt2] CMCF-ID Health
Jacobson, Jared M.; Yin, Jiang; Kitov, Pavel I.; Mulvey, George; Griener, Tom P. et al. (2014). The Crystal Structure of Shiga Toxin Type 2 with Bound Disaccharide Guides the Design of a Heterobifunctional Toxin Inhibitor. Journal of Biological Chemistry 289(2) , 885-894. 10.1074/jbc.m113.518886. [PDB: 4m1u] CMCF-ID Health
Iancu, Cristina V.; Zamoon, Jamillah; Woo, Sang Bum; Aleshin, Alexander; Choe, Jun-yong et al. (2013). Crystal structure of a glucose/H + symporter and its mechanism of action. Proceedings of the National Academy of Sciences of the United States of America 110(44) , 17862-17867. 10.1073/pnas.1311485110. CMCF-ID Health
Huh, Ian; Gene, Robert; Kumaran, Jyothi; MacKenzie, C. Roger; Brooks, Cory L. et al. (2014). In situproteolysis, crystallization and preliminary X-ray diffraction analysis of a VHH that binds listeria internalin B. Acta Crystallographica Section F:Structural Biology Communications 70(11) , 1532-1535. 10.1107/s2053230x1402010x. CMCF-ID Health
Hou, Jinzhao; Townson, Sharon A.; Kovalchin, Joseph T.; Masci, Allyson; Kiner, Olga et al. (2013). Design of a superior cytokine antagonist for topical ophthalmic use. Proceedings of the National Academy of Sciences of the United States of America 110(10) , 3913-3918. 10.1073/pnas.1217996110. [PDB: 4gaf, 4gai] CMCF-ID Health
Hough, Michael A.; Antonyuk, Svetlana V.; Barbieri, Sonia; Rustage, Neil; McKay, Alison L. et al. (2011). Distal-to-Proximal NO Conversion in Hemoproteins: The Role of the Proximal Pocket. Journal of Molecular Biology 405(2) , 395-409. 10.1016/j.jmb.2010.10.035. [PDB: 2xlo, 2xlw] CMCF-ID Health
Hong, Minsun; Lee, Peter S.; Hoffman, Ryan M. B.; Zhu, Xueyong; Krause, Jens C. et al. (2013). Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. Journal of Virology 87(22) , 12471-12480. 10.1128/jvi.01388-13. [PDB: 4m5z] CMCF-ID Health
Higgins, Melanie A.; Whitworth, Garrett E.; El Warry, Nahida; Randriantsoa, Mialy; Samain, Eric et al. (2009). Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases. Journal of Biological Chemistry 284(38) , 26161-26173. 10.1074/jbc.m109.024067. CMCF-ID Health