Publication Beamlines Strategic Pillar
Lin, Yih-Shyan; Park, Jaeok; De Schutter, Joris W.; Huang, Xian Fang; Berghuis, Albert M. et al. (2012). Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. Journal of Medicinal Chemistry 55(7) , 3201-3215. 10.1021/jm201657x. [PDB: 4dem] CMCF-ID Health
Thi, Nhung Nguyen; Offen, Wendy A.; Shareck, François; Davies, Gideon J.; Doucet, Nicolas et al. (2014). Structure and Activity of the Streptomyces coelicolor A3(2) β-N-Acetylhexosaminidase Provides Further Insight into GH20 Family Catalysis and Inhibition. Biochemistry 53(11) , 1789-1800. 10.1021/bi401697j. [PDB: 4c7f] CMCF-ID Health
Keszei, Alexander F. A.; Tang, Xiaojing; McCormick, Craig; Zeqiraj, Elton; Rohde, John R. et al. (2014). Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Molecular and Cellular Biology 34(3) , 362-373. 10.1128/mcb.01360-13. [PDB: 4nkg] CMCF-ID Health
Lobo, Paolo Antonio; Van Petegem, Filip (2009). Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations. Structure 17(11) , 1505-1514. 10.1016/j.str.2009.08.016. [PDB: 3ila, 3im5, 3im6, 3im7] CMCF-ID Health
Kolappan, Subramaniapillai; Tracy, Erin N.; Bakaletz, Lauren O.; Munson, Robert S.; Craig, Lisa et al. (2012). Expression, purification, crystallization and preliminary crystallographic analysis of PilA from the nontypeableHaemophilus influenzaetype IV pilus. Acta Crystallographica Section F Structural Biology and Crystallization Communications 68(3) , 284-287. 10.1107/s1744309111043910. CMCF-ID Health
Little, Dustin J.; Li, Grace; Ing, Christopher; DiFrancesco, Benjamin R.; Bamford, Natalie C. et al. (2014). Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6- N -acetyl- d -glucosamine. Proceedings of the National Academy of Sciences of the United States of America 111(30) , 11013-11018. 10.1073/pnas.1406388111. [PDB: 4p7q, 4p7r] CMCF-ID Health
Campbell, Stephen J.; Edwards, Ross A.; Glover, J.N. Mark (2010). Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1. Structure 18(2) , 167-176. 10.1016/j.str.2009.12.008. [PDB: 3k0h, 3k0k, 3k15, 3k16] CMCF-ID Health
Visschedyk, Danielle; Rochon, Amanda; Tempel, Wolfram; Dimov, Svetoslav; Park, Hee-Won et al. (2012). Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus. Journal of Biological Chemistry 287(49) , 41089-41102. 10.1074/jbc.m112.412809. [PDB: 4fxq, 4gf1] CMCF-ID Health
Shala, Agnesa; Patel, Kevin H.; Golemi-Kotra, Dasantila; Audette, Gerald F. (2013). Expression, purification, crystallization and preliminary X-ray analysis of the receiver domain ofStaphylococcus aureusLytR protein. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(12) , 1418-1421. 10.1107/s1744309113030972. CMCF-ID Health
Kaustov, Lilia; Ouyang, Hui; Amaya, Maria; Lemak, Alexander; Nady, Nataliya et al. (2011). Recognition and Specificity Determinants of the Human Cbx Chromodomains. Journal of Biological Chemistry 286(1) , 521-529. 10.1074/jbc.m110.191411. [PDB: 3h91, 3i91] CMCF-ID Health
Schellenberg, Matthew J; Wu, Tao; Ritchie, Dustin B; Fica, Sebastian; Staley, Jonathan P et al. (2013). A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural and Molecular Biology 20(6) , 728-734. 10.1038/nsmb.2556. [PDB: 4jk7, 4jk8, 4jk9, 4jka, 4jkb, 4jkc, 4jkh] CMCF-ID Health
Karunan Partha, Sarathy; van Straaten, Karin E.; Sanders, David A.R. (2009). Structural Basis of Substrate Binding to UDP-galactopyranose Mutase: Crystal Structures in the Reduced and Oxidized State Complexed with UDP-galactopyranose and UDP. Journal of Molecular Biology 394(5) , 864-877. 10.1016/j.jmb.2009.10.013. [PDB: 3hdq, 3hdy, 3he3] CMCF-ID Health
MacFarlane, Ainsley A.; Orriss, George; Okun, Natalie; Meier, Markus; Klonisch, Thomas et al. (2012). The Pentameric Channel of COMPcc in Complex with Different Fatty Acids. PLoS ONE 7(11) , e48130. 10.1371/journal.pone.0048130. [PDB: 3v2n, 3v2p, 3v2q] CMCF-ID Health
Ukpabi, Georgia; Takayama, Shin-ichi J.; Mauk, A.Grant; Murphy, Michael E.P. (2012). Inactivation of the Heme Degrading Enzyme IsdI by an Active Site Substitution That Diminishes Heme Ruffling. Journal of Biological Chemistry 287(41) , 34179-34188. 10.1074/jbc.m112.393249. [PDB: 4fnh] CMCF-ID Health
Schroeder, Gretchen M.; Wei, Donna; Banfi, Patrizia; Cai, Zhen-Wei; Lippy, Jonathan et al. (2012). Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorganic and Medicinal Chemistry Letters 22(12) , 3951-3956. 10.1016/j.bmcl.2012.04.106. [PDB: 4ehr] CMCF-ID Health