Publication Beamlines Strategic Pillar
Farha, Maya A.; Czarny, Tomasz L.; Myers, Cullen L.; Worrall, Liam J.; French, Shawn et al. (2015). Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proceedings of the National Academy of Sciences of the United States of America 112(35) , 11048-11053. 10.1073/pnas.1511751112. [PDB: 5cqb, 5cqj] CMCF-ID Health
Ernst, Andreas; Avvakumov, George; Tong, Jiefei; Fan, Yihui; Zhao, Yanling et al. (2013). A Strategy for Modulation of Enzymes in the Ubiquitin System. Science 339(6119) , 590-595. 10.1126/science.1230161. [PDB: 3n3k] CMCF-ID Health
Epstein, Linda F.; Chen, Hao; Emkey, Renee; Whittington, Douglas A. (2012). The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. Journal of Biological Chemistry 287(44) , 37447-37457. 10.1074/jbc.m112.391425. [PDB: 4fnz] CMCF-ID Health
Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] CMCF-ID Health
Edwards, Thomas E.; Leibly, David J.; Bhandari, Janhavi; Statnekov, Jacob B.; Phan, Isabelle et al. (2011). Structures of phosphopantetheine adenylyltransferase fromBurkholderia pseudomallei. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1032-1037. 10.1107/s1744309111004349. [PDB: 3k9w] CMCF-ID Health
Eble, Johannes A.; Niland, Stephan; Bracht, Thilo; Mormann, Michael; Peter-Katalinic, Jasna et al. (2009). The α2β1 integrin‐specific antagonist rhodocetin is a cruciform, heterotetrameric molecule. FASEB Journal 23(9) , 2917-2927. 10.1096/fj.08-126763. CMCF-ID Health
Du, Liqin; Luo, Yu (2013). Structure of a filament of stacked octamers of human DMC1 recombinase. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(4) , 382-386. 10.1107/s1744309113005678. [PDB: 4hyy] CMCF-ID Health
Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Yang, Bingwei V.; Doweyko, Lidia M. et al. (2014). Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(24) , 5721-5726. 10.1016/j.bmcl.2014.10.061. [PDB: 4rio] CMCF-ID Health
Dresen, Carola; Lin, Leo Y.-C.; D'Angelo, Igor; Tocheva, Elitza I.; Strynadka, Natalie et al. (2010). A Flavin-dependent Monooxygenase from Mycobacterium tuberculosis Involved in Cholesterol Catabolism. Journal of Biological Chemistry 285(29) , 22264-22275. 10.1074/jbc.m109.099028. [PDB: 3aff] CMCF-ID Health
Doores, Katie J.; Kong, Leopold; Krumm, Stefanie A.; Le, Khoa M.; Sok, Devin et al. (2015). Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope. Journal of Virology 89(2) , 1105-1118. 10.1128/jvi.02905-14. [PDB: 4rnr] CMCF-ID Health
De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] CMCF-ID Health
D’Costa, Vanessa M.; Braun, Virginie; Landekic, Marija; Shi, Rong; Proteau, Ariane et al. (2015). Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports 12(9) , 1508-1518. 10.1016/j.celrep.2015.07.063. [PDB: 5cq9] CMCF-ID Health
Dalrymple, Sean A.; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. (2011). Preliminary X-ray crystallographic studies of UDP-glucose-4-epimerase fromAspergillus nidulans. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(8) , 885-887. 10.1107/s1744309111020914. CMCF-ID Health
Dalrymple, Sean A.; Ko, John; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. et al. (2013). Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase. PLoS ONE 8(10) , e76803. 10.1371/journal.pone.0076803. [PDB: 4lis] CMCF-ID Health
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. [PDB: 4c1r, 4c1s] CMCF-BM, CMCF-ID Health