| Szewczyk, Paul; Tao, Houchao; McGrath, Aaron P.; Villaluz, Mark; Rees, Steven D. et al. (2015). Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallographica Section D Biological Crystallography 71(3) , 732-741. 10.1107/s1399004715000978. [PDB: 4q9i, 4q9j, 4q9l] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gritzalis, Dimitrios; Park, Jaeok; Chiu, Wei; Cho, Hyungjun; Lin, Yih-Shyan et al. (2015). Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic and Medicinal Chemistry Letters 25(5) , 1117-1123. 10.1016/j.bmcl.2014.12.089. [PDB: 4qxs] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Badger, J.; Sridhar, V.; Logan, C.; Hausheer, F.H.; Nienaber, V.L. et al. (2015). Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA. Protein Data Bank: 4rqx. |
CMCF-ID |
PDB Deposition |
Health |
| Muckelbauer, J.K. (2015). CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH BMS-066 AKA 2-METHOXY-N-({6-[3-METHYL-7-(METHYLAMINO)-3,5,8,10-TETRAAZATRICYCLO[7.3.0.0, 6]DODECA-1(9),2(6),4,7,11-PENTAEN-11-YL]PYRIDIN-2-YL}METHY L)ACETAMIDE. Protein Data Bank: 4wov. |
CMCF-ID |
PDB Deposition |
Health |
| Tokarski, John S.; Zupa-Fernandez, Adriana; Tredup, Jeffrey A.; Pike, Kristen; Chang, ChiehYing et al. (2015). Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. Journal of Biological Chemistry 290(17) , 11061-11074. 10.1074/jbc.m114.619502. [PDB: 4wov] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wong, Joyce J. W.; Lu, Jun; Edwards, Ross A.; Frost, Laura S.; Glover, J. N. Mark et al. (2011). Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM. Nucleic Acids Research 39(15) , 6775-6788. 10.1093/nar/gkr296. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Siarheyeva, Alena; Senisterra, Guillermo; Allali-Hassani, Abdellah; Dong, Aiping; Dobrovetsky, Elena et al. (2012). An Allosteric Inhibitor of Protein Arginine Methyltransferase 3. Structure 20(8) , 1425-1435. 10.1016/j.str.2012.06.001. [PDB: 3smq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Flath, Benjamin (2012). Structural characterization of the type II secretion system of Aeromonas hydrophila. Supervisor: Grochulski, Pawel; Howard, Peter. Saskatchewan, Canada: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2012-04-909. |
CMCF-ID |
Masters Thesis |
Health |
| Sweeting, Braden (2014). The structural basis of prion disease susceptibility and the transmission barrier. Supervisor: Pai, Emil F.. Canada, ON: University of Toronto. http://hdl.handle.net/1807/43717. |
CMCF-ID |
Doctoral Thesis |
Health |
| Zamyatkin, Dmitry; Rao, Chandni; Hoffarth, Elesha; Jurca, Gabriela; Rho, Hayeong et al. (2014). Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallographica Section D Biological Crystallography 70(12) , 3099-3109. 10.1107/s1399004714021518. [PDB: 4qpx] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lau, Kelvin; Van Petegem, Filip (2014). Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain. Nature Communications 5(1) . 10.1038/ncomms6397. [PDB: 4p9i] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Krska, Daniel; Ravulapalli, Ravikiran; Fieldhouse, Robert J.; Lugo, Miguel R.; Merrill, A. Rod et al. (2015). C3larvin Toxin, an ADP-ribosyltransferase from Paenibacillus larvae. Journal of Biological Chemistry 290(3) , 1639-1653. 10.1074/jbc.m114.589846. [PDB: 4tr5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kalynych, Sergei; Cherney, Maia; Bostina, Mihnea; Rouiller, Isabelle; Cygler, Miroslaw et al. (2014). Quaternary structure of WzzB and WzzE polysaccharide copolymerases. Protein Science 24(1) , 58-69. 10.1002/pro.2586. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Huh, Ian; Gene, Robert; Kumaran, Jyothi; MacKenzie, C. Roger; Brooks, Cory L. et al. (2014). In situproteolysis, crystallization and preliminary X-ray diffraction analysis of a VHH that binds listeria internalin B. Acta Crystallographica Section F:Structural Biology Communications 70(11) , 1532-1535. 10.1107/s2053230x1402010x. |
CMCF-ID |
Peer-Reviewed Article |
Health |