Publication Beamlines Strategic Pillar
Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Wan, Honghe; Inghrim, Jennifer A.; Zimmermann, Kurt et al. (2011). Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Bioorganic and Medicinal Chemistry Letters 21(5) , 1425-1428. 10.1016/j.bmcl.2011.01.022. [PDB: 3q32] CMCF-ID Health
Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] CMCF-ID Health
Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] CMCF-ID Health
Hehemann, Jan-Hendrik; Law, Adrienne; Redecke, Lars; Boraston, Alisdair B. (2014). The Structure of RdDddP from Roseobacter denitrificans Reveals That DMSP Lyases in the DddP-Family Are Metalloenzymes. PLoS ONE 9(7) , e103128. 10.1371/journal.pone.0103128. [PDB: 4b28] CMCF-ID Materials
Hehemann, Jan-Hendrik; Smyth, Leo; Yadav, Anuj; Vocadlo, David J.; Boraston, Alisdair B. et al. (2012). Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight into the Degradation (of a Polysaccharide from) Red Seaweeds. Journal of Biological Chemistry 287(17) , 13985-13995. 10.1074/jbc.m112.345645. [PDB: 4ak7] CMCF-ID Health
Helliwell, John R.; Mitchell, Edward P. (2015). Synchrotron radiation macromolecular crystallography: science and spin-offs. IUCrJ 2(2) , 283-291. 10.1107/s205225251402795x. CMCF-ID Materials
Herold, J. Martin; Wigle, Tim J.; Norris, Jacqueline L.; Lam, Robert; Korboukh, Victoria K. et al. (2011). Small-Molecule Ligands of Methyl-Lysine Binding Proteins. Journal of Medicinal Chemistry 54(7) , 2504-2511. 10.1021/jm200045v. [PDB: 3p8h] CMCF-ID Health
Hewitt, Stephen N.; Choi, Ryan; Kelley, Angela; Crowther, Gregory J.; Napuli, Alberto J. et al. (2011). Expression of proteins inEscherichia colias fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1006-1009. 10.1107/s1744309111022159. [PDB: 3u40] CMCF-ID Health
He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu et al. (2010). Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature 467(7318) , 991-994. 10.1038/nature09408. CMCF-ID Health
He, Yang; Ning, Tingting; Xie, Tingting; Qiu, Qingchuan; Zhang, Liping et al. (2011). Large-scale production of functional human serum albumin from transgenic rice seeds. Proceedings of the National Academy of Sciences of the United States of America 108(47) , 19078-19083. 10.1073/pnas.1109736108. [PDB: 3sqj] CMCF-ID Health
Higgins, Melanie A.; Ficko-Blean, Elizabeth; Meloncelli, Peter J.; Lowary, Todd L.; Boraston, Alisdair B. et al. (2011). The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate-Antigen-Hydrolyzing Enzymes. Journal of Molecular Biology 411(5) , 1017-1036. 10.1016/j.jmb.2011.06.035. [PDB: 2ygm] CMCF-ID Health
Higgins, Melanie A.; Whitworth, Garrett E.; El Warry, Nahida; Randriantsoa, Mialy; Samain, Eric et al. (2009). Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases. Journal of Biological Chemistry 284(38) , 26161-26173. 10.1074/jbc.m109.024067. CMCF-ID Health
Hong, Minsun; Lee, Peter S.; Hoffman, Ryan M. B.; Zhu, Xueyong; Krause, Jens C. et al. (2013). Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. Journal of Virology 87(22) , 12471-12480. 10.1128/jvi.01388-13. [PDB: 4m5z] CMCF-ID Health
Hoover, Gordon J.; Jørgensen, René; Rochon, Amanda; Bajwa, Vikramjit S.; Merrill, A. Rod et al. (2013). Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants. Biochimica et Biophysica Acta - Proteins and Proteomics 1834(12) , 2663-2671. 10.1016/j.bbapap.2013.09.013. CMCF-ID Agriculture
Hough, Michael A.; Antonyuk, Svetlana V.; Barbieri, Sonia; Rustage, Neil; McKay, Alison L. et al. (2011). Distal-to-Proximal NO Conversion in Hemoproteins: The Role of the Proximal Pocket. Journal of Molecular Biology 405(2) , 395-409. 10.1016/j.jmb.2010.10.035. [PDB: 2xlo, 2xlw] CMCF-ID Health