Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. [PDB: 4ly8, 4m19, 4mlj, 4mlr, 4r53] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Coquelle, Nicolas; Green, Ruth; Glover, J. N. Mark (2011). Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition. Biochemistry 50(21) , 4579-4589. 10.1021/bi2003795. [PDB: 3pxa, 3pxb, 3pxd, 3pxe] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Coquelle, Nicolas; Havali-Shahriari, Zahra; Bernstein, Nina; Green, Ruth; Glover, J. N. Mark et al. (2011). Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proceedings of the National Academy of Sciences of the United States of America 108(52) , 21022-21027. 10.1073/pnas.1112036108. [PDB: 3u7e, 3u7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dalrymple, Sean A.; Ko, John; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. et al. (2013). Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase. PLoS ONE 8(10) , e76803. 10.1371/journal.pone.0076803. [PDB: 4lis] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dalrymple, Sean A.; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. (2011). Preliminary X-ray crystallographic studies of UDP-glucose-4-epimerase fromAspergillus nidulans. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(8) , 885-887. 10.1107/s1744309111020914. |
CMCF-ID |
Peer-Reviewed Article |
Health |
De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dresen, Carola; Lin, Leo Y.-C.; D'Angelo, Igor; Tocheva, Elitza I.; Strynadka, Natalie et al. (2010). A Flavin-dependent Monooxygenase from Mycobacterium tuberculosis Involved in Cholesterol Catabolism. Journal of Biological Chemistry 285(29) , 22264-22275. 10.1074/jbc.m109.099028. [PDB: 3aff] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Yang, Bingwei V.; Doweyko, Lidia M. et al. (2014). Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(24) , 5721-5726. 10.1016/j.bmcl.2014.10.061. [PDB: 4rio] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Du, Liqin; Luo, Yu (2013). Structure of a filament of stacked octamers of human DMC1 recombinase. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(4) , 382-386. 10.1107/s1744309113005678. [PDB: 4hyy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Eble, Johannes A.; Niland, Stephan; Bracht, Thilo; Mormann, Michael; Peter-Katalinic, Jasna et al. (2009). The α2β1 integrin‐specific antagonist rhodocetin is a cruciform, heterotetrameric molecule. FASEB Journal 23(9) , 2917-2927. 10.1096/fj.08-126763. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Edwards, Thomas E.; Leibly, David J.; Bhandari, Janhavi; Statnekov, Jacob B.; Phan, Isabelle et al. (2011). Structures of phosphopantetheine adenylyltransferase fromBurkholderia pseudomallei. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1032-1037. 10.1107/s1744309111004349. [PDB: 3k9w] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Epstein, Linda F.; Chen, Hao; Emkey, Renee; Whittington, Douglas A. (2012). The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. Journal of Biological Chemistry 287(44) , 37447-37457. 10.1074/jbc.m112.391425. [PDB: 4fnz] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ernst, Andreas; Avvakumov, George; Tong, Jiefei; Fan, Yihui; Zhao, Yanling et al. (2013). A Strategy for Modulation of Enzymes in the Ubiquitin System. Science 339(6119) , 590-595. 10.1126/science.1230161. [PDB: 3n3k] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ficko-Blean, Elizabeth; Stuart, Christopher P.; Boraston, Alisdair B. (2011). Structural analysis of CPF_2247, a novel α-amylase from Clostridium perfringens. Proteins: Structure. Function and Bioinformatics 79(10) , 2771-2777. 10.1002/prot.23116. [PDB: 3ren] |
CMCF-ID |
Peer-Reviewed Article |
Health |