Publication Beamlines Strategic Pillar
Penfield, Jonathan S.; Worrall, Liam J.; Strynadka, Natalie C.; Eltis, Lindsay D. (2014). Substrate Specificities and Conformational Flexibility of 3-Ketosteroid 9α-Hydroxylases. Journal of Biological Chemistry 289(37) , 25523-25536. 10.1074/jbc.m114.575886. [PDB: 4qck, 4qdc, 4qdd, 4qdf] CMCF-BM Health
Bailey-Elkin, Ben A.; Knaap, Robert C.M.; Johnson, Garrett G.; Dalebout, Tim J.; Ninaber, Dennis K. et al. (2014). Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression. Journal of Biological Chemistry 289(50) , 34667-34682. 10.1074/jbc.m114.609644. [PDB: 4rez, 4rf0, 4rf1] CMCF-BM Health
Von Kreudenstein, Thomas Spreter; Escobar-Carbrera, Eric; Lario, Paula I.; D’Angelo, Igor; Brault, Karine et al. (2013). Improving biophysical properties of a bispecific antibody scaffold to aid developability. mAbs 5(5) , 646-654. 10.4161/mabs.25632. [PDB: 4bsv, 4bsw] CMCF-BM Health
Persch, Elke; Bryson, Steve; Todoroff, Nickolay K.; Eberle, Christian; Thelemann, Jonas et al. (2014). Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase. ChemMedChem , 1880-1891. 10.1002/cmdc.201402032. [PDB: 4nev] CMCF-BM Health
Jadhav, Pramodkumar; Schatte, Gabriele; Labiuk, Shaunivan; Burnett, Peta-Gaye; Li, Bonnie et al. (2011). Cyclolinopeptide K butanol disolvate monohydrate. Acta Crystallographica Section E: Structure Reports Online 67(9) , o2360-o2361. 10.1107/s1600536811032363. CMCF-BM Health
Frank, Filipp; Hauver, Jesse; Sonenberg, Nahum; Nagar, Bhushan (2012). ArabidopsisArgonaute MID domains use their nucleotide specificity loop to sort small RNAs. EMBO Journal 31(17) , 3588-3595. 10.1038/emboj.2012.204. [PDB: 4g0x] CMCF-BM Health
Murase, Tomohiko; Eugenio, Luiz; Schorr, Melissa; Hussack, Greg; Tanha, Jamshid et al. (2014). Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. Journal of Biological Chemistry 289(4) , 2331-2343. 10.1074/jbc.m113.505917. [PDB: 4nbx, 4nby, 4nc1] CMCF-BM Health
King, Dustin T.; Worrall, Liam J.; Gruninger, Robert; Strynadka, Natalie C. J. (2012). New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition. Journal of the American Chemical Society 134(28) , 11362-11365. 10.1021/ja303579d. [PDB: 4exy, 4ey2, 4eyb, 4eyf, 4eyl] CMCF-BM, CMCF-ID Health
Nam, Sung-Eun; Kim, Apollos C.; Paetzel, Mark (2012). Crystal Structure of Bacillus subtilis Signal Peptide Peptidase A. Journal of Molecular Biology 419(5) , 347-358. 10.1016/j.jmb.2012.03.020. [PDB: 3rst] CMCF-BM Health
Higgins, Melanie A.; Suits, Michael D.; Marsters, Candace; Boraston, Alisdair B. (2014). Structural and Functional Analysis of Fucose-Processing Enzymes from Streptococcus pneumoniae. Journal of Molecular Biology 426(7) , 1469-1482. 10.1016/j.jmb.2013.12.006. [PDB: 4c21, 4c22] CMCF-BM Health
King, Dustin T.; Lameignere, Emilie; Strynadka, Natalie C.J. (2014). Structural Insights into the Lipoprotein Outer Membrane Regulator of Penicillin-binding Protein 1B. Journal of Biological Chemistry 289(27) , 19245-19253. 10.1074/jbc.m114.565879. [PDB: 4q6l, 4q6v, 4q6z] CMCF-BM Health
Nam, Sung-Eun; Paetzel, Mark (2013). Structure of Signal Peptide Peptidase A with C-Termini Bound in the Active Sites: Insights into Specificity, Self-Processing, and Regulation. Biochemistry 52(49) , 8811-8822. 10.1021/bi4011489. [PDB: 4kwb] CMCF-BM Health
Bie, Haiying; Yin, Jiang; He, Xu; Kermode, Allison R; Goddard-Borger, Ethan D et al. (2013). Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology 9(11) , 739-745. 10.1038/nchembio.1357. [PDB: 4mj2, 4mj4] CMCF-BM, CMCF-ID Health
Solomonson, Matthew; Huesgen, Pitter F.; Wasney, Gregory A.; Watanabe, Nobuhiko; Gruninger, Robert J. et al. (2013). Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System. Journal of Biological Chemistry 288(24) , 17782-17790. 10.1074/jbc.m113.462036. [PDB: 4j94, 4kpg] CMCF-BM Health
Singh, Rahul; Grigg, Jason C.; Armstrong, Zachary; Murphy, Michael E.P.; Eltis, Lindsay D. et al. (2012). Distal Heme Pocket Residues of B-type Dye-decolorizing Peroxidase. Journal of Biological Chemistry 287(13) , 10623-10630. 10.1074/jbc.m111.332171. [PDB: 3vec, 3ved, 3vee, 3vef, 3veg] CMCF-BM Health