Publication Beamlines Strategic Pillar
Leung, Chun Yuen; Park, Jaeok; De Schutter, Joris W.; Sebag, Michael; Berghuis, Albert M. et al. (2013). Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. Journal of Medicinal Chemistry 56(20) , 7939-7950. 10.1021/jm400946f. [PDB: 4jvj, 4l2x] CMCF-ID Health
Leung, Kevin Ka Ki; Litchfield, David W.; Shilton, Brian H. (2012). Flavin adenine dinucleotide content of quinone reductase 2: Analysis and optimization for structure–function studies. Analytical Biochemistry 420(1) , 84-89. 10.1016/j.ab.2011.09.011. CMCF-ID Health
Leung, Kevin K.K.; Shilton, Brian H. (2013). Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2. Journal of Biological Chemistry 288(16) , 11242-11251. 10.1074/jbc.m113.457002. CMCF-ID Health
Lewis, Melissa; Meza-Avina, Maria Elena; Wei, Lianhu; Crandall, Ian E.; Bello, Angelica Mara et al. (2011). Novel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate Decarboxylase. Journal of Medicinal Chemistry 54(8) , 2891-2901. 10.1021/jm101642g. [PDB: 3mo7] CMCF-ID Health
Li, Alison Yueh; Lee, Jaeyong; Borek, Dominika; Otwinowski, Zbyszek; Tibbits, Glen F. et al. (2011). Crystal Structure of Cardiac Troponin C Regulatory Domain in Complex with Cadmium and Deoxycholic Acid Reveals Novel Conformation. Journal of Molecular Biology 413(3) , 699-711. 10.1016/j.jmb.2011.08.049. [PDB: 3rv5] CMCF-ID Health
Lin, Yih-Shyan; Park, Jaeok; De Schutter, Joris W.; Huang, Xian Fang; Berghuis, Albert M. et al. (2012). Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. Journal of Medicinal Chemistry 55(7) , 3201-3215. 10.1021/jm201657x. [PDB: 4dem] CMCF-ID Health
Liu, Lili; O'Grady, Christopher; Dalrymple, Sean A.; Prasad, Lata; Dmitriev, Oleg Y. et al. (2009). Crystallization and preliminary X-ray studies of the N-domain of the Wilson disease associated protein. Acta Crystallographica Section F Structural Biology and Crystallization Communications 65(6) , 621-624. 10.1107/s1744309109017023. CMCF-ID Health
Liu, Xiaohu; Chen, Min; Lobo, Paolo; An, Jianghong; Grace Cheng, S.W. et al. (2012). Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL+chronic myeloid leukemia cells to tyrosine kinase inhibitors. Proteomics 12(13) , 2094-2106. 10.1002/pmic.201100553. [PDB: 4esr] CMCF-ID Health
Li, Yang; He, Yujiong; Luo, Yu (2009). Crystal Structure of an Archaeal Rad51 Homologue in Complex with a Metatungstate Inhibitor. Biochemistry 48(29) , 6805-6810. 10.1021/bi900832t. [PDB: 3fyh] CMCF-ID Health
Li, Yang; He, Yujiong; Luo, Yu (2009). Conservation of a conformational switch in RadA recombinase fromMethanococcus maripaludis. Acta Crystallographica Section D Biological Crystallography 65(6) , 602-610. 10.1107/s0907444909011871. [PDB: 3etl, 3ew9, 3ewa] CMCF-ID Health
Lobo, Paolo A.; Kimlicka, Lynn; Tung, Ching-Chieh; Van Petegem, Filip (2011). The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching. Structure 19(6) , 790-798. 10.1016/j.str.2011.03.016. CMCF-ID Health
Lobo, Paolo Antonio; Van Petegem, Filip (2009). Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations. Structure 17(11) , 1505-1514. 10.1016/j.str.2009.08.016. [PDB: 3ila, 3im5, 3im6, 3im7] CMCF-ID Health
Loewen, Peter C.; Didychuk, Allison L.; Switala, Jacek; Perez-Luque, Rosa; Fita, Ignacio et al. (2012). Structure ofPisum sativumRubisco with bound ribulose 1,5-bisphosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(1) , 10-14. 10.1107/s1744309112047549. [PDB: 4hhh, 4mkv] CMCF-ID Health
Lovering, Andrew L; Lin, Leo Y-C; Sewell, Edward W; Spreter, Thomas; Brown, Eric D et al. (2010). Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis. Nature Structural and Molecular Biology 17(5) , 582-589. 10.1038/nsmb.1819. [PDB: 3l7i, 3l7j, 3l7k, 3l7l, 3l7m] CMCF-ID Health
MacFarlane, Ainsley A.; Orriss, George; Okun, Natalie; Meier, Markus; Klonisch, Thomas et al. (2012). The Pentameric Channel of COMPcc in Complex with Different Fatty Acids. PLoS ONE 7(11) , e48130. 10.1371/journal.pone.0048130. [PDB: 3v2n, 3v2p, 3v2q] CMCF-ID Health