Publication Beamlines Strategic Pillar
Lee, Ho Jun; Lairson, Luke L.; Rich, Jamie R.; Lameignere, Emilie; Wakarchuk, Warren W. et al. (2011). Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni. Journal of Biological Chemistry 286(41) , 35922-35932. 10.1074/jbc.m111.261172. [PDB: 2x61] CMCF-ID Health
Lee, Ho Jun; Rakić, Bojana; Gilbert, Michel; Wakarchuk, Warren W.; Withers, Stephen G. et al. (2009). Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase OatWY from Neisseria meningitidis. Journal of Biological Chemistry 284(36) , 24501-24511. 10.1074/jbc.m109.006049. [PDB: 2wlg] CMCF-ID Health
Leung, Charles Chung Yun; Gong, Zihua; Chen, Junjie; Glover, J. N. Mark (2011). Molecular Basis of BACH1/FANCJ Recognition by TopBP1 in DNA Replication Checkpoint Control. Journal of Biological Chemistry 286(6) , 4292-4301. 10.1074/jbc.m110.189555. [PDB: 3al2, 3al3] CMCF-ID Health
Leung, Charles Chung Yun; Kellogg, Elizabeth; Kuhnert, Anja; Hänel, Frank; Baker, David et al. (2009). Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIβ binding protein 1. Protein Science , 162-167. 10.1002/pro.290. [PDB: 3jve] CMCF-ID Health
Leung, Charles Chung Yun; Sun, Luxin; Gong, Zihua; Burkat, Michael; Edwards, Ross et al. (2013). Structural Insights into Recognition of MDC1 by TopBP1 in DNA Replication Checkpoint Control. Structure 21(8) , 1450-1459. 10.1016/j.str.2013.06.015. [PDB: 3ueo] CMCF-ID Health
Leung, Chun Yuen; Park, Jaeok; De Schutter, Joris W.; Sebag, Michael; Berghuis, Albert M. et al. (2013). Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. Journal of Medicinal Chemistry 56(20) , 7939-7950. 10.1021/jm400946f. [PDB: 4jvj, 4l2x] CMCF-ID Health
Leung, Kevin Ka Ki; Litchfield, David W.; Shilton, Brian H. (2012). Flavin adenine dinucleotide content of quinone reductase 2: Analysis and optimization for structure–function studies. Analytical Biochemistry 420(1) , 84-89. 10.1016/j.ab.2011.09.011. CMCF-ID Health
Leung, Kevin K.K.; Shilton, Brian H. (2013). Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2. Journal of Biological Chemistry 288(16) , 11242-11251. 10.1074/jbc.m113.457002. CMCF-ID Health
Lewis, Melissa; Meza-Avina, Maria Elena; Wei, Lianhu; Crandall, Ian E.; Bello, Angelica Mara et al. (2011). Novel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate Decarboxylase. Journal of Medicinal Chemistry 54(8) , 2891-2901. 10.1021/jm101642g. [PDB: 3mo7] CMCF-ID Health
Li, Alison Yueh; Lee, Jaeyong; Borek, Dominika; Otwinowski, Zbyszek; Tibbits, Glen F. et al. (2011). Crystal Structure of Cardiac Troponin C Regulatory Domain in Complex with Cadmium and Deoxycholic Acid Reveals Novel Conformation. Journal of Molecular Biology 413(3) , 699-711. 10.1016/j.jmb.2011.08.049. [PDB: 3rv5] CMCF-ID Health
Lin, Yih-Shyan; Park, Jaeok; De Schutter, Joris W.; Huang, Xian Fang; Berghuis, Albert M. et al. (2012). Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. Journal of Medicinal Chemistry 55(7) , 3201-3215. 10.1021/jm201657x. [PDB: 4dem] CMCF-ID Health
Liu, Lili; O'Grady, Christopher; Dalrymple, Sean A.; Prasad, Lata; Dmitriev, Oleg Y. et al. (2009). Crystallization and preliminary X-ray studies of the N-domain of the Wilson disease associated protein. Acta Crystallographica Section F Structural Biology and Crystallization Communications 65(6) , 621-624. 10.1107/s1744309109017023. CMCF-ID Health
Liu, Tong; Ramesh, Arati; Ma, Zhen; Ward, Sarah K; Zhang, Limei et al. (2006). CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator. Nature Chemical Biology 3(1) , 60-68. 10.1038/nchembio844. HXMA Health
Liu, Xiaohu; Chen, Min; Lobo, Paolo; An, Jianghong; Grace Cheng, S.W. et al. (2012). Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL+chronic myeloid leukemia cells to tyrosine kinase inhibitors. Proteomics 12(13) , 2094-2106. 10.1002/pmic.201100553. [PDB: 4esr] CMCF-ID Health
Li, Yang; He, Yujiong; Luo, Yu (2009). Crystal Structure of an Archaeal Rad51 Homologue in Complex with a Metatungstate Inhibitor. Biochemistry 48(29) , 6805-6810. 10.1021/bi900832t. [PDB: 3fyh] CMCF-ID Health