| Sietsema, D.V. (2025). Crystal Structure of human cyclic GMP-AMP synthase (cGAS) in complex with compound 36; (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5-(2-hydroxyethoxy)pyrimidin-2-yl)methanone. Protein Data Bank: 9mdc. |
CMCF-ID |
PDB Deposition |
Health |
| Spurlino, J.C.; Milligan, C. (2025). An RORgt Inverse agonist for treatment of Psoriasis. Protein Data Bank: 9n9l. |
CMCF-ID |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2b: 6-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine. Protein Data Bank: 9edy. |
CMCF-BM |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile. Protein Data Bank: 9edx. |
CMCF-BM |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1f: 7-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine. Protein Data Bank: 9edw. |
CMCF-BM |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1e: 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine-7-carbonitrile. Protein Data Bank: 9edv. |
CMCF-ID |
PDB Deposition |
Health |
| Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Bar Ziv, T.; Chen, A.; Knox, J.E. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G12R, and CypA. Protein Data Bank: 9bgc. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS Q61L, and CypA. Protein Data Bank: 9bgd. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS Q61H, and CypA. Protein Data Bank: 9bgb. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS Q61R, and CypA. Protein Data Bank: 9bg8. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G13D, and CypA. Protein Data Bank: 9bg5. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS Q61K, and CypA. Protein Data Bank: 9bg3. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Compound-10, KRAS G12V, and CypA. Protein Data Bank: 9bg2. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS WT, and CypA. Protein Data Bank: 9bg0. |
CMCF-ID |
PDB Deposition |
Health |