Publication Beamlines Strategic Pillar
Marta Girona Alarcón1,+, Willy Kuo1,+, Mattia Humbel2, Christine Tanner2, Luca Fardin3, Britta Bausch1, Yann Decker4, Irene Spera5, Griffin Rodgers2, Hans Deyhle2, Alberto Bravin6, Masato Hoshino7, Arash Panahifar8,9, Kentaro Uesugi7, Sergei Gasilov10, Petr Pleskač11, Yuansheng Zhang1, Diane de Zélicourt1, Amandine Brenna11, Ahmad Kamal Hamid12, Pooya Razzaghi Khamesi1, Britta Engelhardt11, Steven T. Proulx11, Bert Müller2, Vartan Kurtcuoglu (2025). In vivo imaging of central nervous system fluid spaces using synchrotron radiation based micro computed tomography. None. https://arxiv.org/abs/2507.03186. BMIT-ID Health
Allgayer, Raphaela; Kabir, Reefah Fahmida; Bergeron, Alexandre; Demers, Philippe; Mantovani, Diego et al. (2025). A collagen-based laboratory model to mimic sex-specific features of calcific aortic valve disease. Acta Biomaterialia 194, 204-218. 10.1016/j.actbio.2025.01.034. SXRMB Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Chen, Joseph M.; Lin, Vincent Y. W.; Le, Trung N.; Spiegel, Jennifer L.; Ungar, Omer J. et al. (2025). Synchrotron‐Based Trauma Assessment of Robotic Electrode Insertions in Cochlear Implantation. Laryngoscope . 10.1002/lary.32254. BMIT Health
Chen, Yinshan; Baviriseaty, Sruthika; Thool, Prajwal; Gautreau, Jonah; Yawman, Phillip D. et al. (2025). Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography Techniques and AI-Enabled Image Analysis. Pharmaceutical Research 42(1) , 203-217. 10.1007/s11095-024-03812-0. BMIT-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Dahlan, Nuraina Anisa; Chiok, Kim Lam R.; Tabil, Xavier L.; Duan, Xiaoman; Banerjee, Arinjay et al. (2025). Development and characterization of a decellularized lung ECM-based bioink for bioprinting and fabricating a lung model. Biomaterials Advances 177, 214428. 10.1016/j.bioadv.2025.214428. BMIT-ID Health
Daneshamouz, Sana; Saadati, Shaghayegh; Zhu, Sishi; Kalugin, Denis; Shoker, Ahmed et al. (2025). Investigation on the Detoxification of Indoxyl Sulfate (IS) and Indole-3-Acetic Acid (IAA) Protein-Bound Uremic Toxins (PBUTs) Using Trametes versicolor Biocompatible Laccase: In Situ Synchrotron Imaging, Experimental and Computational Studies. Applied Biochemistry and Biotechnology . 10.1007/s12010-025-05235-y. BMIT-ID Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] CMCF-ID Health
Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] CMCF-ID Health
Hallin, Karin; Agrawal, Sumit; Ladak, Hanif M.; Rask‐Andersen, Helge; Li, Hao et al. (2025). Cochlear Implantation and Facial Nerve Stimulation: Clinical and Anatomic Correlations. Laryngoscope . 10.1002/lary.70143. BMIT Health