Publication Beamlines Strategic Pillar
Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS WT, and CypA. Protein Data Bank: 9bg0. CMCF-ID Health
Tomlinson, A.C.A.; Chen, A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-2, KRAS G12V, and CypA. Protein Data Bank: 9bg4. CMCF-ID Health
Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-4, KRAS G12C, and CypA. Protein Data Bank: 9bfw. CMCF-ID Health
Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-19, KRAS G12C, and CypA. Protein Data Bank: 9bfv. CMCF-ID Health
Tomlinson, A.C.A.; Saldajeno-Concar, M.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G12V, and CypA. Protein Data Bank: 9bg6. CMCF-ID Health
Ye, Q.; Vance, T.D.R.; Davies, P.L. (2025). Crystal structure of Repeats-in-Toxin-like domain from Aeromonas hydrophila. Protein Data Bank: 9cse. CMCF-ID Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] CMCF-BM Health
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. CMCF-BM Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39Q mutant. Protein Data Bank: 9dfq. CMCF-BM Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K23/24Q mutant. Protein Data Bank: 9dfp. CMCF-BM Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K31Q mutant. Protein Data Bank: 9dfo. CMCF-BM Health