| Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-19, KRAS G12C, and CypA. Protein Data Bank: 9bfv. |
CMCF-ID |
PDB Deposition |
Health |
| Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. |
CMCF-ID |
PDB Deposition |
Health |
| Hu, Z.; Klupt, K.; Zechel, D.; Jia, Z.; Howe, G. et al. (2025). Crystal Structure of AroC. Protein Data Bank: 9eh6. |
CMCF-ID |
PDB Deposition |
Health |
| Lee, J.; Miranda-Zaragoza, B.; Rodriguez-Almazan, C.; Strynadka, N.C.J. (2025). Thermus thermophilus HB27 laccase (Tth-Lac) mutant with partial deletion of beta-hairpin sequence. Protein Data Bank: 9cpm. |
CMCF-ID |
PDB Deposition |
Health |
| Ezekiel, S.; Park, J. (2025). Structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D-C247L) in complex with isopentenyl pyrophosphate. Protein Data Bank: 9csl. |
CMCF-ID |
PDB Deposition |
Health |
| Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). The Crystal Structure of Glucosyltransferase TcdB from Clostridioides difficile. Protein Data Bank: 8y2l. |
CMCF-ID |
PDB Deposition |
Health |
| Higgins, M.A.; Ryan, K.S. (2025). Piperazate synthase (PipS) in complex with haem. Protein Data Bank: 9ebk. |
CMCF-ID |
PDB Deposition |
Health |
| Rogers, C.M.; Langelaan, D.N. (2025). Crystal Structure of TREX1 Homolog Plex9.1. Protein Data Bank: 9mrc. |
CMCF-ID |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1e: 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine-7-carbonitrile. Protein Data Bank: 9edv. |
CMCF-ID |
PDB Deposition |
Health |
| Ireland, K.A.; Davis, K.M. (2025). OvoM from Sulfuricurvum sp. isolate STB_99, an ovothiol-biosynthetic N-methyltransferase in complex with 5-thiohistidine and SAH. Protein Data Bank: 9bxn. |
CMCF-ID |
PDB Deposition |
Health |
| Muna, T.H.; Prehna, G. (2025). Crystal structure of Esub1. Protein Data Bank: 8vsq. |
CMCF-ID |
PDB Deposition |
Health |
| Sietsema, D.V. (2025). Crystal Structure of human cyclic GMP-AMP synthase (cGAS) in complex with compound 36; (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5-(2-hydroxyethoxy)pyrimidin-2-yl)methanone. Protein Data Bank: 9mdc. |
CMCF-ID |
PDB Deposition |
Health |
| Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |