Publication Beamlines Strategic Pillar
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Health
Loundagin, Lindsay L.; Harrison, Kim D.; Cooper, David M. L. (2025). Balanced Basic Multicellular Unit Activity in Cortical Bone of Ovariohysterectomized Rabbits. Calcified Tissue International 116(1) . 10.1007/s00223-025-01426-1. BMIT-ID Health
Hallin, Karin; Agrawal, Sumit; Ladak, Hanif M.; Rask‐Andersen, Helge; Li, Hao et al. (2025). Cochlear Implantation and Facial Nerve Stimulation: Clinical and Anatomic Correlations. Laryngoscope . 10.1002/lary.70143. BMIT Health
Hemmings, Mark; Zieliński, Michał; Golkar, Tolou; Blanchet, Jonathan; Pistofidis, Angelos et al. (2025). Enzyme-mediated aminoglycoside resistance without target mimicry. Communications Chemistry 8(1) . 10.1038/s42004-025-01666-0. [PDB: 9mgu] CMCF-ID Health
Abdoli, Amirabbas; Yang, Zhihan; Odeh‐Ahmed, Abdullah; Bednova, Olga; Lemieux, Bruno et al. (2025). Probing the extent of importin‐α targeting of the TAF8 NLS by eliminating its cationic net‐charge. Protein Science 34(9) . 10.1002/pro.70272. [PDB: 9cl8, 9cle, 9clf, 9clg] CMCF-ID Health
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Health
Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] CMCF-BM Health
Li, Hao; Staxäng, Karin; Agrawal, Sumit; Ladak, Hanif M.; Rask-Andersen, Helge et al. (2025). The Multifaceted Human Round Window Anatomical Aspects and Clinical Relevance. Otology and Neurotology 46(8) , 984-990. 10.1097/mao.0000000000004560. BMIT-ID Health
Dahlan, Nuraina Anisa; Chiok, Kim Lam R.; Tabil, Xavier L.; Duan, Xiaoman; Banerjee, Arinjay et al. (2025). Development and characterization of a decellularized lung ECM-based bioink for bioprinting and fabricating a lung model. Biomaterials Advances 177, 214428. 10.1016/j.bioadv.2025.214428. BMIT-ID Health
Marta Girona Alarcón1,+, Willy Kuo1,+, Mattia Humbel2, Christine Tanner2, Luca Fardin3, Britta Bausch1, Yann Decker4, Irene Spera5, Griffin Rodgers2, Hans Deyhle2, Alberto Bravin6, Masato Hoshino7, Arash Panahifar8,9, Kentaro Uesugi7, Sergei Gasilov10, Petr Pleskač11, Yuansheng Zhang1, Diane de Zélicourt1, Amandine Brenna11, Ahmad Kamal Hamid12, Pooya Razzaghi Khamesi1, Britta Engelhardt11, Steven T. Proulx11, Bert Müller2, Vartan Kurtcuoglu (2025). In vivo imaging of central nervous system fluid spaces using synchrotron radiation based micro computed tomography. None. https://arxiv.org/abs/2507.03186. BMIT-ID Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health