Publication Beamlines Strategic Pillar
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] CMCF-BM Health
Krishnan, Shreya S; Shen, Yao; O’Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W et al. (2025). Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. Nucleic Acids Research 53(11) . 10.1093/nar/gkaf472. [PDB: 9d5l] CMCF-BM Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Zhao, Feipeng; Zhang, Shumin; Wang, Shuo; Reid, Joel W.; Xia, Wei et al. (2025). Anion sublattice design enables superionic conductivity in crystalline oxyhalides. Science 390(6769) , 199-204. 10.1126/science.adt9678. CMCF-BM, SXRMB Materials
Zhu, X.; Moineau, S.; Shi, R. (2025). Crystal structure of the HEPN family member AbiV (P212121 space group). Protein Data Bank: 9bj5. CMCF-BM Agriculture
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2025). Crystal structure of human ribonuclease 7 (RNase 7) in complex with 5'-adenosine monophosphate (5'-AMP). Protein Data Bank: 9csn. CMCF-BM Agriculture
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2025). Crystal structure of human ribonuclease 7 (RNase 7, HsR7). Protein Data Bank: 9csm. CMCF-BM Agriculture
Tran, N.; Frenette, A.; Holyoak, T. (2025). Thomasclavelia ramosa Immunoglobulin A Protease Middle (Protease) Domain with C-terminal Domain #1 (Metal Chelated and Zinc Supplemented). Protein Data Bank: 9ekn. CMCF-BM Agriculture
Tran, N.; Frenette, A.; Holyoak, T. (2025). Thomasclavelia ramosa Immunoglobulin A Protease Middle (Protease) Domain with C-terminal Domain #1 (Metal Chelated). Protein Data Bank: 9ekm. CMCF-BM Agriculture
Tran, N.; Frenette, A.; Holyoak, T. (2025). Thomasclavelia ramosa Immunoglobulin A Protease Middle (Protease) Domain with C-terminal Domain #1 (Crystallized as Purified). Protein Data Bank: 9ekk. CMCF-BM Agriculture
Shaik, M.M.; Brennan, D. (2025). Crystal structure of human 15-PGDH in complex with small molecule compound 1. Protein Data Bank: 9pfl. CMCF-BM Agriculture