Publication Beamlines Strategic Pillar
Whittington, D.A. (2025). Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 14. Protein Data Bank: 9n3o. CMCF-BM Health
Tran, N.; Holyoak, T. (2025). Crystal Structure of the Gemella haemolysans Immunoglobulin A1 Protease Trypsin-Like Domain. Protein Data Bank: 9ect. CMCF-BM Health
Kimani, S.; Dong, A.; Hoffmann, L.; Nemec, V.; Ackloo, S. et al. (2025). Crystal structure of the human WDR5 in complex with LH168 compound. Protein Data Bank: 9d5z. CMCF-BM Health
Langelier, M.F.; Pascal, J.M. (2025). Human PARP1 ART domain bound to NAD+ analog benzamide adenine dinucleotide and ADP-ribose. Protein Data Bank: 9dmc. CMCF-BM Health
Langelier, M.F.; Pascal, J.M. (2025). Human PARP1 ART domain bound to NAD+ analogs benzamide adenine dinucleotide and carba-NAD+. Protein Data Bank: 9bpy. CMCF-BM Health
Grainger, R.; Colussi, D.C.; Noble, M.; Junop, M.; Stathopulos, P.B. et al. (2025). Human mitochondrial calcium uniporter crystal structure (residues 74-165 resolved) with lithium. Protein Data Bank: 8urg. CMCF-BM Health
Rogers, C.M.; Langelaan, D.N. (2025). Crystal Structure of TREX1 Homolog Plex9.1 bound to ssDNA. Protein Data Bank: 9mrd. CMCF-BM Health
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2b: 6-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine. Protein Data Bank: 9edy. CMCF-BM Health
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile. Protein Data Bank: 9edx. CMCF-BM Health
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1f: 7-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine. Protein Data Bank: 9edw. CMCF-BM Health
Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] CMCF-ID Health
Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] CMCF-ID Health
Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] CMCF-ID Health
Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph et al. (2025). Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis. Journal of Medicinal Chemistry 68(8) , 8713-8728. 10.1021/acs.jmedchem.5c00390. [PDB: 9n9l] CMCF-ID Health
Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] CMCF-ID Health