Publication Beamlines Strategic Pillar
Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] CMCF-ID Health
Hu, Zhenyu; Klupt, Kody; Zechel, David L.; Jia, Zongchao; Howe, Graeme W. et al. (2025). Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities using Sequence Similarity Networks. ChemBioChem . 10.1002/cbic.202500065. [PDB: 9eh6] CMCF-ID Environment
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Miranda-Zaragoza, Beatriz; Huerta-Miranda, Guillermo A.; García-García, Wendy I.; Hernández-Álvarez, Elizabeth; Solano-Peralta, Alejandro et al. (2025). Structure-Function Relationship of the β-Hairpin of Thermus thermophilus HB27 Laccase. International Journal of Molecular Sciences 26(2) , 735. 10.3390/ijms26020735. [PDB: 9cpm] CMCF-ID Health
Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2025). Structural and functional analysis of SAM-dependent N-methyltransferases involved in ovoselenol and ovothiol biosynthesis. Structure . 10.1016/j.str.2024.12.020. CMCF-ID Health
Mendez, Alex; Bolling, Cydni; Taylor, Shane; Makumire, Stanley; Staker, Bart et al. (2025). Structure of Plasmodium vivax N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy. Acta Crystallographica Section F:Structural Biology Communications 81(1) , 1-10. 10.1107/s2053230x24011348. [PDB: 5v0w] CMCF-ID Health
Kin S. YANG; Hang CHU; Solomon H. REISBERG; Wai Yan CHOY; Brian P. BESTVATER et al. (2025). Reversible lysine covalent modifiers of cdk2 and uses thereof. Patent Number: WO2025090658. CMCF-ID Health
Jean-Philippe Julien; Taylor Sicard; Anthony Semesi; Bebhinn Treanor; Tiantian Zhao et al. (2025). Nanoparticle platform for antibody and vaccine delivery. Patent Number: US20250114475A1. CMCF-ID Health
Stephen G. Withers; Peter Rahfeld; Jayachandran Kizhakkedathu (2025). Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith. Patent Number: US20250011749A1. CMCF-ID Agriculture
Delker, S.L.; Edwards, T.E.; Abendroth, J. (2025). Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine. Protein Data Bank: 9d03. CMCF-ID Agriculture
Delker, S.L.; Edwards, T.E.; Abendroth, J. (2025). Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014883 (2R)-4-(ethenesulfonyl)-1-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}-2-[(prop-2-yn-1-yloxy)methyl]piperazine. Protein Data Bank: 9d02. CMCF-ID Agriculture
Park, J.; Akanmori, N. (2025). Crystal structure of human ribokinase in complex with K+, Mg2+, and AMPCP. Protein Data Bank: 9cva. CMCF-ID Agriculture
Park, J.; Akanmori, N.N. (2025). Crystal structure of human ribokinase in complex with K+. Protein Data Bank: 9cwu. CMCF-ID Agriculture