Publication Beamlines Strategic Pillar
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Chen, Yinshan; Baviriseaty, Sruthika; Thool, Prajwal; Gautreau, Jonah; Yawman, Phillip D. et al. (2025). Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography Techniques and AI-Enabled Image Analysis. Pharmaceutical Research 42(1) , 203-217. 10.1007/s11095-024-03812-0. BMIT-BM Health
Chen, Joseph M.; Lin, Vincent Y. W.; Le, Trung N.; Spiegel, Jennifer L.; Ungar, Omer J. et al. (2025). Synchrotron‐Based Trauma Assessment of Robotic Electrode Insertions in Cochlear Implantation. Laryngoscope . 10.1002/lary.32254. BMIT Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Allgayer, Raphaela; Kabir, Reefah Fahmida; Bergeron, Alexandre; Demers, Philippe; Mantovani, Diego et al. (2025). A collagen-based laboratory model to mimic sex-specific features of calcific aortic valve disease. Acta Biomaterialia 194, 204-218. 10.1016/j.actbio.2025.01.034. SXRMB Health
Marta Girona Alarcón1,+, Willy Kuo1,+, Mattia Humbel2, Christine Tanner2, Luca Fardin3, Britta Bausch1, Yann Decker4, Irene Spera5, Griffin Rodgers2, Hans Deyhle2, Alberto Bravin6, Masato Hoshino7, Arash Panahifar8,9, Kentaro Uesugi7, Sergei Gasilov10, Petr Pleskač11, Yuansheng Zhang1, Diane de Zélicourt1, Amandine Brenna11, Ahmad Kamal Hamid12, Pooya Razzaghi Khamesi1, Britta Engelhardt11, Steven T. Proulx11, Bert Müller2, Vartan Kurtcuoglu (2025). In vivo imaging of central nervous system fluid spaces using synchrotron radiation based micro computed tomography. None. https://arxiv.org/abs/2507.03186. BMIT-ID Health
LYNSEY CORTNEY BENT (2025). EVALUATING RISK OF LEAD EXPOSURE IN SCAVENGING SPECIES LINKED TO BIGGAME HUNTING IN SASKATCHEWAN, CANADA. Supervisor: Kirsty Gurney. Saskatchewan, Canada: University of Saskatchewan. https://hdl.handle.net/10388/16738. BMIT-ID Health
Khassan, Oleg (2025). Unraveling the Regulation of Plant and Yeast Plastin Proteins: A Structural Determination Study. Supervisor: Haji-Ghassemi, Omid. Alberter, Canada: University of Calgary. https://hdl.handle.net/1880/120616. CMCF Health
Kin S. YANG; Hang CHU; Solomon H. REISBERG; Wai Yan CHOY; Brian P. BESTVATER et al. (2025). Reversible lysine covalent modifiers of cdk2 and uses thereof. Patent Number: WO2025090658. CMCF-ID Health
Jean-Philippe Julien; Taylor Sicard; Anthony Semesi; Bebhinn Treanor; Tiantian Zhao et al. (2025). Nanoparticle platform for antibody and vaccine delivery. Patent Number: US20250114475A1. CMCF-ID Health
Ye, Q.; Vance, T.D.R.; Davies, P.L. (2025). Crystal structure of Repeats-in-Toxin-like domain from Aeromonas hydrophila. Protein Data Bank: 9cse. CMCF-ID Health
Whittington, D.A. (2025). Crystal structure of truncated USP1:UAF1 in complex with compound 18. Protein Data Bank: 9n9y. CMCF-BM Health
Whittington, D.A. (2025). Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 14. Protein Data Bank: 9n3o. CMCF-BM Health
Tran, N.; Holyoak, T. (2025). Crystal Structure of the Gemella haemolysans Immunoglobulin A1 Protease Trypsin-Like Domain. Protein Data Bank: 9ect. CMCF-BM Health