Publication Beamlines Strategic Pillar
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Dahlan, Nuraina Anisa; Chiok, Kim Lam R.; Tabil, Xavier L.; Duan, Xiaoman; Banerjee, Arinjay et al. (2025). Development and characterization of a decellularized lung ECM-based bioink for bioprinting and fabricating a lung model. Biomaterials Advances 177, 214428. 10.1016/j.bioadv.2025.214428. BMIT-ID Health
Daneshamouz, Sana; Saadati, Shaghayegh; Zhu, Sishi; Kalugin, Denis; Shoker, Ahmed et al. (2025). Investigation on the Detoxification of Indoxyl Sulfate (IS) and Indole-3-Acetic Acid (IAA) Protein-Bound Uremic Toxins (PBUTs) Using Trametes versicolor Biocompatible Laccase: In Situ Synchrotron Imaging, Experimental and Computational Studies. Applied Biochemistry and Biotechnology . 10.1007/s12010-025-05235-y. BMIT-ID Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Di Lello, Paola; Wells, Marta M.; Davis, Ben; Daniels, Zoe; Garner, Thomas P. et al. (2026). Targeting PTPN22 at Nonorthosteric Binding Sites─A Fragment Approach. ACS Omega . 10.1021/acsomega.5c11028. [PDB: 9yg0, 9yg1, 9yg3] CMCF-BM Health
Ereño-Orbea, June; Pang, Lijuan; Sicard, Taylor; Nycholat, Corwin; Cui, Hong et al. (2025). Molecular Insights into the Engagement of High-Affinity Sialylated Ligands to Human CD22. JACS Au . 10.1021/jacsau.5c01013. [PDB: 9rm3, 9ro7, 9rob] CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Pang, Lijuan; Sicard, Taylor; Nycholat, Corwin; Cui, Hong et al. (2025). Molecular Insights into the Engagement of High-Affinity Sialylated Ligands to Human CD22. JACS Au . 10.1021/jacsau.5c01013. [PDB: 9rm3, 9ro7, 9rob] CMCF-BM, CMCF-ID Health
Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] CMCF-ID Health
Ezekiel, S.; Park, J. (2025). Structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D-C247L) in complex with isopentenyl pyrophosphate. Protein Data Bank: 9csl. CMCF-ID Health
Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). Crystal structure of serine hydroxymethyltransferase 1. Protein Data Bank: 8xnd. CMCF-ID Health
Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). The Crystal Structure of Glucosyltransferase TcdB from Clostridioides difficile. Protein Data Bank: 8y2l. CMCF-ID Health
Fong, J.K.; Cordeiro, R.L.; Van Petegem, F.; Brumer, H. (2026). Structure of glyoxal oxidase from Fusarium graminearum at 1.28 Angstroms resolution. Protein Data Bank: 9n3u. CMCF-ID Health
Fontano, E.; Suto, R.K.; Olland, A.M. (2025). Structure of PAK1 in complex with compound 31. Protein Data Bank: 9d4y. CMCF-ID Health
Foroughi, Farangis; Aulakh, Gurpreet Kaur; Krapohl, David; Norlin, Börje; Menk, Ralf Hendrik et al. (2025). A Gaussian fitting-based analysis method for multiple image radiography with integrated angular calibration, MIR2. Physics in Medicine and Biology . 10.1088/1361-6560/ae22ba. BMIT Health
Forrester, T.J.B.; Kimber, M.S. (2025). human ClpP - Bortezomib - A192E / E196R. Protein Data Bank: 9dql. CMCF-ID Health