| Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Chen, Yinshan; Baviriseaty, Sruthika; Thool, Prajwal; Gautreau, Jonah; Yawman, Phillip D. et al. (2025). Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography Techniques and AI-Enabled Image Analysis. Pharmaceutical Research 42(1) , 203-217. 10.1007/s11095-024-03812-0. |
BMIT-BM |
Peer-Reviewed Article |
Health |
| Chen, Joseph M.; Lin, Vincent Y. W.; Le, Trung N.; Spiegel, Jennifer L.; Ungar, Omer J. et al. (2025). Synchrotron‐Based Trauma Assessment of Robotic Electrode Insertions in Cochlear Implantation. Laryngoscope . 10.1002/lary.32254. |
BMIT |
Peer-Reviewed Article |
Health |
| Black, Tallan; Boseley, Rhiannon E.; Quirk, Amanda; Young, Kaylen M.; Lunardi-Baccetto, Sarah et al. (2026). Adult Rat Offspring Exposed to THC during Gestation Exhibit Distinct Biomolecular Changes Identified by X-ray Fluorescence Imaging and Fourier Transform Infrared Spectroscopy in Cortico-Limbic Circuits. ACS Chemical Neuroscience . 10.1021/acschemneuro.5c00752. |
BIOXAS-IMAGING, MID-IR |
Peer-Reviewed Article |
Health |
| Black, Tallan; Boseley, Rhiannon E.; Quirk, Amanda; Young, Kaylen M.; Lunardi-Baccetto, Sarah et al. (2026). Adult Rat Offspring Exposed to THC during Gestation Exhibit Distinct Biomolecular Changes Identified by X-ray Fluorescence Imaging and Fourier Transform Infrared Spectroscopy in Cortico-Limbic Circuits. ACS Chemical Neuroscience . 10.1021/acschemneuro.5c00752. |
BIOXAS-IMAGING, MID-IR |
Peer-Reviewed Article |
Health |
| Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Bekkering, Ezra T.; Yoo, Randy; Hailemariam, Sophia; Heide, Fabian; Ivanochko, Danton et al. (2025). Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity . 10.1016/j.immuni.2025.09.014. [PDB: 9n7k] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Allgayer, Raphaela; Kabir, Reefah Fahmida; Bergeron, Alexandre; Demers, Philippe; Mantovani, Diego et al. (2025). A collagen-based laboratory model to mimic sex-specific features of calcific aortic valve disease. Acta Biomaterialia 194, 204-218. 10.1016/j.actbio.2025.01.034. |
SXRMB |
Peer-Reviewed Article |
Health |
| Abdoli, Amirabbas; Yang, Zhihan; Odeh‐Ahmed, Abdullah; Bednova, Olga; Lemieux, Bruno et al. (2025). Probing the extent of importin‐α targeting of the TAF8 NLS by eliminating its cationic net‐charge. Protein Science 34(9) . 10.1002/pro.70272. [PDB: 9cl8, 9cle, 9clf, 9clg] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| MURHULA, Espoir M.; Wang, Wennie; Lambiv Dzemua, Gideon; Lim, Suk Gyu; Schatte, Gabriele et al. (2025). Unveiling the Amphoteric Surface Reactivity of Montebrasite using Spectroscopic and First-Principles Methods. Patent Number: 10.26434/chemrxiv-2025-cvj65. |
VLS-PGM |
Conference Proceeding |
Environment |
| Simpson, Rachel M. L. (2025). Lead exposure in Corinth and Stymphalos, Greece, in late antiquity: A chemical investigation of archaeological skeletal remains. Supervisor: Garvie-Lok, Sandra. Alberta, Canada: University of Alberta. https://doi.org/10.7939/83044. |
BIOXAS-IMAGING |
Doctoral Thesis |
Environment |
| Deng, Tianyang (2026). Developing Bioanalytical Platforms for Studying Cyanobacteria with Vibrational Spectroscopy and Hyperspectral Imaging. Supervisor: Greener, Jesse; Vincent, Warwick. Quebec, Canada: Université Laval. https://hdl.handle.net/20.500.11794/180405. |
MID-IR |
Doctoral Thesis |
Environment |
| Bishop, Brendan Alexander (2025). Non-traditional sources of critical minerals from the Western Canada Sedimentary Basin. Supervisor: Robbins, Leslie. Saskatchewan, Canada: University of Regina. https://hdl.handle.net/10294/16769. |
HXMA |
Doctoral Thesis |
Environment |