Publication Beamlines Strategic Pillar
Uguen, Mélanie; Shell, Devan J.; Silva, Madhushika; Deng, Yu; Li, Fengling et al. (2025). Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells. Nature Communications 16(1) . 10.1038/s41467-025-57005-3. [PDB: 9cuw, 9cux] CMCF-BM Health
Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] CMCF-ID Health
Van Schepdael, Matthew; Asakereh, Iman; Colautti, Jake; Gierys, Andrew J.; Sachar, Kartik et al. (2026). Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release. Nature Communications . 10.1038/s41467-025-68138-w. [PDB: 9mvg] CMCF-BM Health
Vara, Brandon A.; Lim, Jongwon; Moure, Casey J.; Schneider, Sebastian E.; Yeung, Charles S. et al. (2026). Discovery and In Vivo Evaluation of Aryl Ether YAP1/TEAD Inhibitors for the Treatment of Hippo-Driven Malignancies. Journal of Medicinal Chemistry 69(4) , 4303-4316. 10.1021/acs.jmedchem.5c02997. [PDB: 9yk2] CMCF-BM Health
Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] CMCF-ID Health
Wang, Mingyu; Du, Grace; Yongo‐Luwawa, Charity; Lu, Angelina; Kinrade, Brett et al. (2025). Peptide‐based ligand antagonists block a Vibrio cholerae adhesin. FEBS Letters . 10.1002/1873-3468.70231. [PDB: 9y9w, 9ybq] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] CMCF-ID Health
Balind, Kathryn; Ezzati, Milad; Picard, Aude; Gélinas, Yves (2025). Exploring the affinity and selectivity of sedimentary mackinawite (FeS) towards natural organic matter. Geochimica et Cosmochimica Acta 405, 98-113. 10.1016/j.gca.2025.07.009. SM Environment
Bauer, Robert P. C.; Rodriguez, Danny; Pathak, Santanu; Tse, John S. (2025). Capturing Hydrate Formation Processes in Tetrahydrofuran/Water Mixtures with Temperature Resolved In Situ Synchrotron X-ray Diffraction and Infrared Spectroscopy. Journal of Physical Chemistry Letters , 5160-5167. 10.1021/acs.jpclett.5c00576. BXDS-WHE, FAR-IR, HXMA Environment
Bechtold, Emily K.; Xin, Danhui; Pacheco, Maricia; Toner, Brandy M.; Arnold, William A. et al. (2025). Diverse Cooccurring Metabolisms Support Sulfur and Methane Cycling in Wetland Surficial Sediments. Journal of Geophysical Research: Biogeosciences 130(9) . 10.1029/2024jg008478. SXRMB Environment
Bejaoui, Salma; Billinghurst, Brant E; Boersma, Christiaan; Esposito, Vincent J (2025). Experimental and Anharmonic Theoretical Spectroscopic Benchmarks of Nitrogenated and Doubly-Nitrogenated Polycyclic Heterocycles. Monthly Notices of the Royal Astronomical Society . 10.1093/mnras/staf1901. FAR-IR Environment
Brinkman, Donald B.; López, J. Andrés; Erickson, Gregory M.; Eberle, Jaelyn J.; Muñoz, Xochitl et al. (2025). Fishes from the Upper Cretaceous Prince Creek Formation, North Slope of Alaska, and their palaeobiogeographical significance. Papers in Palaeontology 11(3) . 10.1002/spp2.70014. CLS-APS Environment
Carriere, Charly; Delanoë, Alexis; Gin, Stéphane; Gardes, Emmanuel; Monnet, Isabelle et al. (2025). Effect of a cement-bentonite grout on AVM glass alteration and C-steel corrosion at nanometer scale. Corrosion Engineering Science and Technology . 10.1177/1478422x241310412. SM Environment
Cook, Brian Kawenski; Beatty, Karsyn; Woolcock, Luke; Zuin, Lucia; Gibson, Charlotte E. et al. (2025). An investigation into the role of alkaline scrubbing in spodumene flotation using X-Ray Absorption Near-Edge Structure (XANES) spectroscopy. Canadian Metallurgical Quarterly , 1-13. 10.1080/00084433.2025.2566580. VLS-PGM Environment