| Higgins, M.A.; Ryan, K.S. (2025). Piperazate synthase (PipS) in complex with haem. Protein Data Bank: 9ebk. |
CMCF-ID |
PDB Deposition |
Health |
| Rogers, C.M.; Langelaan, D.N. (2025). Crystal Structure of TREX1 Homolog Plex9.1. Protein Data Bank: 9mrc. |
CMCF-ID |
PDB Deposition |
Health |
| Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1e: 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine-7-carbonitrile. Protein Data Bank: 9edv. |
CMCF-ID |
PDB Deposition |
Health |
| Ireland, K.A.; Davis, K.M. (2025). OvoM from Sulfuricurvum sp. isolate STB_99, an ovothiol-biosynthetic N-methyltransferase in complex with 5-thiohistidine and SAH. Protein Data Bank: 9bxn. |
CMCF-ID |
PDB Deposition |
Health |
| Muna, T.H.; Prehna, G. (2025). Crystal structure of Esub1. Protein Data Bank: 8vsq. |
CMCF-ID |
PDB Deposition |
Health |
| Sietsema, D.V. (2025). Crystal Structure of human cyclic GMP-AMP synthase (cGAS) in complex with compound 36; (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5-(2-hydroxyethoxy)pyrimidin-2-yl)methanone. Protein Data Bank: 9mdc. |
CMCF-ID |
PDB Deposition |
Health |
| Kin S. YANG; Hang CHU; Solomon H. REISBERG; Wai Yan CHOY; Brian P. BESTVATER et al. (2025). Reversible lysine covalent modifiers of cdk2 and uses thereof. Patent Number: WO2025090658. |
CMCF-ID |
Patent |
Health |
| Jean-Philippe Julien; Taylor Sicard; Anthony Semesi; Bebhinn Treanor; Tiantian Zhao et al. (2025). Nanoparticle platform for antibody and vaccine delivery. Patent Number: US20250114475A1. |
CMCF-ID |
Patent |
Health |
| Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS
G12D
aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] |
CMCF-ID |
Peer-Reviewed Article |
Health |