Publication Beamlines Strategic Pillar
Higgins, M.A.; Ryan, K.S. (2025). Piperazate synthase (PipS) in complex with haem. Protein Data Bank: 9ebk. CMCF-ID Health
Forrester, T.J.B.; Kimber, M.S. (2025). human ClpP - Bortezomib - A192E / E196R. Protein Data Bank: 9dql. CMCF-ID Health
Forrester, T.J.B.; Kimber, M.S. (2025). human ClpP - Apo - A192E / E196R. Protein Data Bank: 9dqk. CMCF-ID Health
Fontano, E.; Suto, R.K.; Olland, A.M. (2025). Structure of PAK1 in complex with compound 31. Protein Data Bank: 9d4y. CMCF-ID Health
Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). Crystal structure of serine hydroxymethyltransferase 1. Protein Data Bank: 8xnd. CMCF-ID Health
Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). The Crystal Structure of Glucosyltransferase TcdB from Clostridioides difficile. Protein Data Bank: 8y2l. CMCF-ID Health
Ezekiel, S.; Park, J. (2025). Structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D-C247L) in complex with isopentenyl pyrophosphate. Protein Data Bank: 9csl. CMCF-ID Health
Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. CMCF-ID Health
Chen, A.; Tomlinson, A.C.A.; Bieder, R.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G12C, and CypA. Protein Data Bank: 9bga. CMCF-ID Health
Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] CMCF-BM Agriculture
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Agriculture
Rolfe, Nicolas; Myskiw, Dustin; Patton, Matthew T.; Forrester, Taylor J. B.; Kimber, Matthew S. et al. (2025). Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes. Biochemistry 64(17) , 3735-3744. 10.1021/acs.biochem.5c00213. [PDB: 9nxl] CMCF-BM Agriculture
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Agriculture
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Agriculture
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health