Publication Beamlines Strategic Pillar
Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] CMCF-BM Health
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] CMCF-BM Health
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Tian, Yuqing; Worrall, Liam J.; Sim, Lyann; Liu, Feng; Nasseri, Seyed A. et al. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis 14(17) , 13497-13508. 10.1021/acscatal.4c03643. [PDB: 9awt, 9ay8, 9ayu] CMCF-BM, CMCF-ID Health
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health
Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. CMCF-BM, CMCF-ID Health
Zhou, Yuebiao; Aliagas, Ignacio; Wang, Shumei; Li, Chun Sing; Liu, Zhiguo et al. (2024). Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorganic and Medicinal Chemistry Letters , 130026. 10.1016/j.bmcl.2024.130026. [PDB: 9dc8, 9dc9] CMCF-BM Health
Kenward, Calem Austin (2024). Structural and functional characterization of key proteins essential to the lifecycle of severe acute respiratory syndrome coronavirus 2. Supervisor: Strynadka, Natalie. University of British Columbia. http://hdl.handle.net/2429/88954. CMCF-BM Health
Jason Rolfe; Mehran Khodabandeh; Zaccary ALPERSTEIN; Seyed Ali Saberali; Hazem MSLATI et al. (2024). Protease inhibitors and methods of using same. Patent Number: WO2024130411A1. CMCF-BM Health
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of K46 acetylated GABARAP in complex with the LIR of TP53INP2/DOR. Protein Data Bank: 8t33. CMCF-BM Health
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form. Protein Data Bank: 8vbw. CMCF-BM Health
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Cephalexin) inhibited form. Protein Data Bank: 8vbv. CMCF-BM Health
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its apo form. Protein Data Bank: 8vbt. CMCF-BM Health
Chi, C.B.; Liang, Z.D.; Huo, B.Q.; Hu, C.X.; Sun, Q.Y. et al. (2024). Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin. Protein Data Bank: 8j5v. CMCF-BM Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. CMCF-BM Health