Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. |
CMCF-ID |
PDB Deposition |
Health |
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). GH5_4 endo-beta(1,3/1,4)-glucanase E331A from Segatella copri in complex with cellotriose. Protein Data Bank: 9bmk. |
CMCF-ID |
PDB Deposition |
Health |
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). Surface glycan-binding protein A (SGBP-A, SusD-like) from a mixed-linkage beta-glucan utilization locus in Segatella copri in complex with cellopentaose. Protein Data Bank: 9bal. |
CMCF-ID |
PDB Deposition |
Health |
Corbett, B.W.; Suits, M.D. (2024). Iron and Copper bound HftA from Treponema denticola. Protein Data Bank: 8t7m. |
CMCF-ID |
PDB Deposition |
Health |
Corbett, B.W.; Suits, M.D. (2024). Copper bound HftA from Treponema denticola. Protein Data Bank: 8t7l. |
CMCF-ID |
PDB Deposition |
Health |
Cooper, David M. L.; Andronowski, Janna M.; Wei, Xuan; Taylor, Joshua T. (2024). Three-Dimensional Microstructural Imaging of Bone. In Sam D. Stout, Christian Crowder(Ed.), Bone Histology: A Biological Anthropological Perspective. CRC Press. , 393-441 10.4324/9781003385608-12. |
BMIT-BM, BMIT-ID |
Book / Chapter |
Health |
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Chu, Y.; Zhai, Y.; Fan, X.; Fu, S.; Li, J. et al. (2024). Structure of a triple-helix region of human Collagen type XVII from Trautec. Protein Data Bank: 8zmv. |
CMCF-ID |
PDB Deposition |
Health |
Chu, Y.; Zhai, Y.; Fan, X.; Fu, S.; Li, J. et al. (2024). Structure of a triple-helix region of human Collagen type XVII from Trautec. Protein Data Bank: 8zmo. |
CMCF-ID |
PDB Deposition |
Health |
Chu, Y.; Zhai, Y.; Fan, X.; Fu, S.; Li, J. et al. (2024). Structure of a triple-helix region of human Collagen type IV from Trautec. Protein Data Bank: 8zmm. |
CMCF-ID |
PDB Deposition |
Health |
Cho, Timothy HS (2024). Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli. Supervisor: Raivio, Tracy. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-kpc4-mn64. |
CMCF-BM |
Doctoral Thesis |
Health |
Chi, C.B.; Liang, Z.D.; Huo, B.Q.; Hu, C.X.; Sun, Q.Y. et al. (2024). Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin. Protein Data Bank: 8j5v. |
CMCF-BM |
PDB Deposition |
Health |