Publication Beamlines Strategic Pillar
Blocka, Carter; Fan Ding, Xiao; Zhu, Ning; Zhang, Lifeng (2024). Experimental investigation of dynamic drying in single pharmaceutical granules containing acetaminophen or carbamazepine using synchrotron X-ray micro computed tomography. International Journal of Pharmaceutics 665, 124664. 10.1016/j.ijpharm.2024.124664. BMIT-BM Health
Bon, Christopher G.; Grigg, Jason C.; Lee, Jaeyong; Robb, Craig S.; Caveney, Nathanael A. et al. (2024). Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. Journal of Structural Biology 216(2) , 108086. 10.1016/j.jsb.2024.108086. [PDB: 8vbt, 8vbv, 8vbw] CMCF-BM Health
Boseley, Rhiannon E.; Sylvain, Nicole J.; Peeling, Lissa; Kelly, Michael E.; Pushie, M. Jake et al. (2024). A review of concepts and methods for FTIR imaging of biomarker changes in the post-stroke brain. Biochimica et Biophysica Acta - Biomembranes 1866(3) , 184287. 10.1016/j.bbamem.2024.184287. MID-IR Health
Brown, Alyssa; Zhu, MengYu; Rohani, Alireza; Ladak, Hanif; Agrawal, Sumit K. et al. (2024). Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy. Laryngoscope 134(6) , 2879-2888. 10.1002/lary.31259. BMIT-ID Health
Chen, Joseph M.; Lin, Vincent Y. W.; Le, Trung N.; Spiegel, Jennifer L.; Ungar, Omer J. et al. (2025). Synchrotron‐Based Trauma Assessment of Robotic Electrode Insertions in Cochlear Implantation. Laryngoscope . 10.1002/lary.32254. BMIT Health
Chen, Yinshan; Baviriseaty, Sruthika; Thool, Prajwal; Gautreau, Jonah; Yawman, Phillip D. et al. (2025). Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography Techniques and AI-Enabled Image Analysis. Pharmaceutical Research 42(1) , 203-217. 10.1007/s11095-024-03812-0. BMIT-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] CMCF-ID Health
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Cummer, Rebecca; Grosjean, Félix; Bolteau, Raphaël; Vasegh, Seyed Ehsan; Veyron, Simon et al. (2024). Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile toxin B. Applied Spectroscopy Reviews . 10.26434/chemrxiv-2024-2cf6g-v2. [PDB: 9bja] CMCF-ID Health
Cyr, Patrick; Fader, Lee D.; Burch, Jason D.; Pike, Kelly A.; Sietsema, Daniel V. et al. (2024). Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization. ACS Medicinal Chemistry Letters 15(12) , 2201-2209. 10.1021/acsmedchemlett.4c00471. [PDB: 9mdc] CMCF-ID Health
Daneshamouz, Sana; Saadati, Shaghayegh; Zhu, Sishi; Kalugin, Denis; Shoker, Ahmed et al. (2025). Investigation on the Detoxification of Indoxyl Sulfate (IS) and Indole-3-Acetic Acid (IAA) Protein-Bound Uremic Toxins (PBUTs) Using Trametes versicolor Biocompatible Laccase: In Situ Synchrotron Imaging, Experimental and Computational Studies. Applied Biochemistry and Biotechnology . 10.1007/s12010-025-05235-y. BMIT-ID Health
Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. CMCF Health