| Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS
G12D
aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| Stephen G. Withers; Peter Rahfeld; Jayachandran Kizhakkedathu (2025). Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith. Patent Number: US20250011749A1. |
CMCF-ID |
Patent |
Agriculture |
| Dementiev, A.A.; Michino, M.; Vendome, J.; Ginn, J.; Bryk, R. et al. (2024). Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series. Protein Data Bank: 8u0q. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Fraser, B.J.; Dong, A.; Ilyassov, O.; Kenney, T.; Li, Y.Y. et al. (2024). Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide. Protein Data Bank: 8vis. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain. Protein Data Bank: 8svh. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 in complex with 53BP1 Tudor domain. Protein Data Bank: 8svg. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Judge, R.A.; Longenecker, K.L. (2025). Crystal structure of TNF alpha in complex with compound 4. Protein Data Bank: 9ojs. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Judge, R.A.; Longenecker, K.L.; Bian, Z. (2025). Crystal structure of TNF alpha in complex with compound 19. Protein Data Bank: 9ok6. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Krausser, C. et al. (2025). Crystal structure of the human DCAF1 WDR domain in complex with OICR-40156. Protein Data Bank: 9ply. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Knudson-Goerner, E.J.; Boraston, A.B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae.. Protein Data Bank: 9nhf. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Li, F.K.K.; Strynadka, N.C.J. (2024). Crystal structure of S. aureus TarL N-terminal domain. Protein Data Bank: 8v33. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Lin, C.S.; Murphy, M.E. (2024). Crystal structure of the peptidoglycan O-acetylesterase Ape1 (amino acids 22-392) from Campylobacter jejuni. Protein Data Bank: 8gld. |
CMCF-ID |
PDB Deposition |
Agriculture |