Publication Beamlines Strategic Pillar
Sychantha, D.; Prehna, G.; Wright, G.D. (2024). Crystal structure of NikA in complex Ni-AMA. Protein Data Bank: 8spm. CMCF-BM Agriculture
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of GABARAP in complex with the LIR of NSs4. Protein Data Bank: 8t2m. CMCF-BM Agriculture
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2024). Crystal structure of a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families. Protein Data Bank: 8g9a. CMCF-BM Agriculture
Penner, T.V.; Prehna, G. (2024). Crystal structure of Sel-1 repeat protein LceB from Legionella pneumophila. Protein Data Bank: 8sxq. CMCF-BM Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 13). Protein Data Bank: 8t5r. CMCF-BM Agriculture
Cho, Timothy HS (2024). Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli. Supervisor: Raivio, Tracy. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-kpc4-mn64. CMCF-BM Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health
Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] CMCF-ID Health
Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] CMCF-ID Health
Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] CMCF-ID Health