Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] |
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Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] |
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Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szn. |
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PDB Deposition |
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Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szm. |
CMCF-BM |
PDB Deposition |
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Mabanglo, M.F.; Wilson, B.J.; Alvarez, H.G.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40333. Protein Data Bank: 9b9h. |
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PDB Deposition |
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Mabanglo, M.F.; Wilson, B.J.; Krausser, C.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40407. Protein Data Bank: 9b9t. |
CMCF-BM |
PDB Deposition |
Health |
Mabanglo, M.F.; Wilson, B.J.; Mamai, A.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40792. Protein Data Bank: 9b9w. |
CMCF-BM |
PDB Deposition |
Health |
Mabanglo, M.F.; Wilson, B.J.; Srivastava, S.; Al-awar, R.; Vedadi, M. et al. (2024). Crystal structure of the binary complex of DCAF1 and WDR5. Protein Data Bank: 9ba2. |
CMCF-BM |
PDB Deposition |
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Muna, Tasneem Hassan; Rutbeek, Nicole R; Horne, Julia; Lao, Ying W; Krokhin, Oleg V et al. (2024). The phage protein paratox is a multifunctional metabolic regulator of Streptococcus. Nucleic Acids Research . 10.1093/nar/gkae1200. [PDB: 8vsq] |
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Nasseri, Seyed Amirhossein; Lazarski, Aleksander C.; Lemmer, Imke L.; Zhang, Chloe Y.; Brencher, Eva et al. (2024). An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature . 10.1038/s41586-024-07574-y. [PDB: 8tdi] |
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Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] |
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Picard, M.-E.; Grenier, G.; Despres, P.C.; Dube, A.K.; Landry, C.R. et al. (2024). Crystal structure of the yeast cytosine deaminase (yCD) E64V-M100W heterodimer. Protein Data Bank: 8vlm. |
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Rogers, C.M.; Langelaan, D.N. (2025). Crystal Structure of TREX1 Homolog Plex9.1 bound to ssDNA. Protein Data Bank: 9mrd. |
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PDB Deposition |
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Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] |
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Saran, A.; Zeytuni, N. (2024). PorX primitive orthorhombic crystal form. Protein Data Bank: 8ted. |
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