Publication Beamlines Strategic Pillar
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2024). The Crystal Structure of TGF beta R2 kinase domain from Biortus.. Protein Data Bank: 8ygz. CMCF-BM Health
Xu, C.; Chung, I.Y.W.; Cygler, M. (2024). Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide. Protein Data Bank: 8sr6. CMCF-BM Health
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2024). The Crystal Structure of USP8 from Biortus.. Protein Data Bank: 8y9a. CMCF-BM Health
Krishnamurthy, H.; Zhuang, N.; Qiang, D.; Wu, Y.; Klein, D.J. et al. (2024). Structure of SARS-Cov2 3CLPro in complex with Compound 27. Protein Data Bank: 8ute. CMCF-BM Health
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2024). Crystal structure of a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families. Protein Data Bank: 8g9a. CMCF-BM Agriculture
Penner, T.V.; Prehna, G. (2024). Crystal structure of Sel-1 repeat protein LceB from Legionella pneumophila. Protein Data Bank: 8sxq. CMCF-BM Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 13). Protein Data Bank: 8t5r. CMCF-BM Agriculture
Jason Rolfe; Mehran Khodabandeh; Zaccary ALPERSTEIN; Seyed Ali Saberali; Hazem MSLATI et al. (2024). Protease inhibitors and methods of using same. Patent Number: WO2024130411A1. CMCF-BM Health
Kenward, Calem Austin (2024). Structural and functional characterization of key proteins essential to the lifecycle of severe acute respiratory syndrome coronavirus 2. Supervisor: Strynadka, Natalie. University of British Columbia. http://hdl.handle.net/2429/88954. CMCF-BM Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Krishnan, Shreya S; Shen, Yao; O’Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W et al. (2025). Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. Nucleic Acids Research 53(11) . 10.1093/nar/gkaf472. CMCF-BM Health
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health