| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D. (2024). PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).. Protein Data Bank: 8v8h. |
CMCF-ID |
PDB Deposition |
Health |
| Gruninger, Robert J.; Kevorkova, Maya; Low, Kristin E.; Jones, Darryl R.; Worrall, Liam et al. (2024). Structural, Biochemical, and Phylogenetic Analysis of Bacterial and Fungal Carbohydrate Esterase Family 15 Glucuronoyl Esterases in the Rumen. Protein Journal 43(4) , 910-922. 10.1007/s10930-024-10221-0. [PDB: 8tru, 8trx, 8tse] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 glucuronoyl esterase from Ruminococcus flavefaciens. Protein Data Bank: 8tse. |
CMCF-ID |
PDB Deposition |
Health |
| Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 glucuronoyl esterase from Piromyces rhizinflatus. Protein Data Bank: 8trx. |
CMCF-ID |
PDB Deposition |
Health |
| Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 from Fibrobacter succinogenes subsp. succinogenes S85. Protein Data Bank: 8tru. |
CMCF-ID |
PDB Deposition |
Health |
| Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Golisch, Benedikt; Cordeiro, Rosa Lorizolla; Fraser, Alexander S.C.; Briggs, Jonathon; Stewart, William A. et al. (2024). The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri. Journal of Biological Chemistry 300(9) , 107625. 10.1016/j.jbc.2024.107625. [PDB: 9bal, 9bmk] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ghosh, K. (2024). Human CK1 Delta Kinase structure bound to Inhibitor. Protein Data Bank: 8izc. |
CMCF-ID |
PDB Deposition |
Health |
| Gajiwala, K.S.; Greasley, S.E.; Ferre, R.A.; Liu, W.; Stewart, A.E. et al. (2024). Structure of SARS-CoV-2 Mpro mutant (T21I,S144A,T304I) in complex with Nirmatrelvir (PF-07321332). Protein Data Bank: 9aum. |
CMCF-ID |
PDB Deposition |
Health |
| Furuzono, T.; Orita, T.; Nomura, A.; Adachi, T. (2024). HIV-1 integrase core domain in complex with compound 5. Protein Data Bank: 8zh4. |
CMCF-ID |
PDB Deposition |
Health |
| Fraser, B.J.; Dong, A.; Ilyassov, O.; Seitova, A.; Li, Y. et al. (2024). Crystal structure of TMPRSS11D S368A complexed with its own zymogen activation motif. Protein Data Bank: 9dpf. |
CMCF-ID |
PDB Deposition |
Health |
| Fraser, B.J.; Dong, A.; Ilyassov, O.; Kenney, T.; Li, Y.Y. et al. (2024). Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide. Protein Data Bank: 8vis. |
CMCF-ID |
PDB Deposition |
Agriculture |