Publication Beamlines Strategic Pillar
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] CMCF-BM, CMCF-ID Health
Kassardjian, A.; Julien, J.P. (2024). Crystal structure of humanized 44H10 Fab Version 22 in complex with HLA-DR (HLA-DRA*01:01/HLA-DRB1*04:01). Protein Data Bank: 9b7b. CMCF-ID Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Gajiwala, K.S.; Greasley, S.E.; Ferre, R.A.; Liu, W.; Stewart, A.E. et al. (2024). Structure of SARS-CoV-2 Mpro mutant (T21I,S144A,T304I) in complex with Nirmatrelvir (PF-07321332). Protein Data Bank: 9aum. CMCF-ID Health
Zhu, Yuao; Yurgelonis, Irina; Noell, Stephen; Yang, Qingyi; Guan, Shunjie et al. (2024). In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Science Advances 10(30) . 10.1126/sciadv.adl4013. [PDB: 9aum] CMCF-ID Health
Ireland, K.A.; Davis, K.M. (2024). EgtB-IV from Crocosphaera subtropica, an ergothioneine-biosynthetic type IV sulfoxide synthase in complex with hercynine. Protein Data Bank: 8vih. CMCF-ID Health
Ireland, K.A.; Davis, K.M. (2024). EgtB-IV from Geminocystis sp. isolate SKYG4, an ergothioneine-biosynthetic type IV sulfoxide synthase in complex with hercynine. Protein Data Bank: 8vig. CMCF-ID Health
Chu, Y.; Zhai, Y.; Fan, X.; Fu, S.; Li, J. et al. (2024). Structure of a triple-helix region of human Collagen type XVII from Trautec. Protein Data Bank: 8zmv. CMCF-ID Health
Wallweber, H.; Hsu, P.L. (2024). Crystal structure of Para.09 bound to TREM2. Protein Data Bank: 8t59. CMCF-ID Health
Schroeter, K.L.; Forrester, T.J.B.; Kimber, M.S.; Seah, S.Y.K. (2024). Structure of steroid hydratase from Comamonas testosteroni. Protein Data Bank: 8vwr. CMCF-ID Health
Schroeter, Kurt L.; Rolfe, Nicolas; Forrester, Taylor J.B.; Kimber, Matthew S.; Seah, Stephen Y.K. et al. (2024). Shy is a proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain. Journal of Biological Chemistry 300(8) , 107509. 10.1016/j.jbc.2024.107509. [PDB: 8vwr] CMCF-ID Health
Kelsey Sivick GAUTHIER; Nigel Pelham Clinton Walker; Xiaoning ZHAO; John Lippincott (2024). Antibodies to tigit. Patent Number: US20240182570A1. CMCF-ID Health
Furuzono, T.; Orita, T.; Nomura, A.; Adachi, T. (2024). HIV-1 integrase core domain in complex with compound 5. Protein Data Bank: 8zh4. CMCF-ID Health
Adachi, Kaoru; Manabe, Tomoyuki; Yamasaki, Takayuki; Suma, Akira; Orita, Takuya et al. (2024). Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety. Bioorganic and Medicinal Chemistry Letters 110, 129864. 10.1016/j.bmcl.2024.129864. [PDB: 8zh4] CMCF-ID Health
Veyron, S.; Cummer, R. (2024). C. difficile Tcdb cysteine protease domain in complex with IP6. Protein Data Bank: 9bja. CMCF-ID Health