Publication Beamlines Strategic Pillar
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). GH5_4 endo-beta(1,3/1,4)-glucanase E331A from Segatella copri in complex with cellotriose. Protein Data Bank: 9bmk. CMCF-ID Health
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). Surface glycan-binding protein A (SGBP-A, SusD-like) from a mixed-linkage beta-glucan utilization locus in Segatella copri in complex with cellopentaose. Protein Data Bank: 9bal. CMCF-ID Health
Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. CMCF-ID Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] CMCF-ID Health
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Critton, D.A. (2024). Crystal structure of monkey TLR7 ectodomain with compound 14. Protein Data Bank: 8s9h. CMCF-ID Health
Cummer, Rebecca; Grosjean, Félix; Bolteau, Raphaël; Vasegh, Seyed Ehsan; Veyron, Simon et al. (2024). Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile toxin B. Applied Spectroscopy Reviews . 10.26434/chemrxiv-2024-2cf6g-v2. [PDB: 9bja] CMCF-ID Health
Cygler, M.; Boniecki, M.T. (2024). Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2. Protein Data Bank: 8tvt. CMCF-ID Health
Cyr, Patrick; Fader, Lee D.; Burch, Jason D.; Pike, Kelly A.; Sietsema, Daniel V. et al. (2024). Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization. ACS Medicinal Chemistry Letters 15(12) , 2201-2209. 10.1021/acsmedchemlett.4c00471. [PDB: 9mdc] CMCF-ID Health
Czapalay, Elyse S.; Soleimanian, Yasamin; Stobbs, Jarvis A.; Marangoni, Alejandro G. (2025). Plant tissue-based scaffolds filled with oil function as adipose tissue mimetics. Current Research in Food Science 10, 101002. 10.1016/j.crfs.2025.101002. BMIT-BM Agriculture
Dai, Hongliu; Sun, Tianxiao; Zhou, Jigang; Wang, Jian; Chen, Zhangsen et al. (2024). Unraveling chemical origins of dendrite formation in zinc-ion batteries via in situ/operando X-ray spectroscopy and imaging. Nature Communications 15(1) . 10.1038/s41467-024-52651-5. SM Materials
Daneshamouz, Sana; Saadati, Shaghayegh; Zhu, Sishi; Kalugin, Denis; Shoker, Ahmed et al. (2025). Investigation on the Detoxification of Indoxyl Sulfate (IS) and Indole-3-Acetic Acid (IAA) Protein-Bound Uremic Toxins (PBUTs) Using Trametes versicolor Biocompatible Laccase: In Situ Synchrotron Imaging, Experimental and Computational Studies. Applied Biochemistry and Biotechnology . 10.1007/s12010-025-05235-y. BMIT-ID Health
Daniel-Ivad, Phillip (2024). Crystallographic and biochemical characterization of key steps in reductasporine and capuramycin biosynthesis. Supervisor: Ryan, Katherine S.. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/87410. CMCF Health