| Vu, Binh T.; Dominique, Romyr; Fahr, Bruce J.; Li, Hongju H.; Fry, David C. et al. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.4c00379. [PDB: 9br4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila
RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Zhu, Yuao; Yurgelonis, Irina; Noell, Stephen; Yang, Qingyi; Guan, Shunjie et al. (2024). In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Science Advances 10(30) . 10.1126/sciadv.adl4013. [PDB: 9aum] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Jean-Philippe Julien; Taylor Sicard; Anthony Semesi; Bebhinn Treanor; Tiantian Zhao et al. (2025). Nanoparticle platform for antibody and vaccine delivery. Patent Number: US20250114475A1. |
CMCF-ID |
Patent |
Health |
| Judit Anido Folgueira; Patricia Anne Giblin; Robin Matthew Hallett; Jeanne Magram; Naimish PANDYA et al. (2024). Combination of lif inhibitors and platinum-based antineoplastic agents for use in treating cancer. Patent Number: AU2024204564A1. |
CMCF-ID |
Patent |
Health |
| Kelsey Sivick GAUTHIER; Nigel Pelham Clinton Walker; Xiaoning ZHAO; John Lippincott (2024). Antibodies to tigit. Patent Number: US20240182570A1. |
CMCF-ID |
Patent |
Health |
| Kin S. YANG; Hang CHU; Solomon H. REISBERG; Wai Yan CHOY; Brian P. BESTVATER et al. (2025). Reversible lysine covalent modifiers of cdk2 and uses thereof. Patent Number: WO2025090658. |
CMCF-ID |
Patent |
Health |
| Marcelo CYPEL; Aizhou WANG; Shafique Keshavjee; Stephen G. Withers; Peter Rahfeld et al. (2024). Enzymatic compositions for carbohydrate antigen cleavage on donor organs, methods and uses associated therewith. Patent Number: US20240294895A1. |
CMCF-ID |
Patent |
Health |
| Abendroth, J.; Lorimer, D.D.; Vu, B.; Takana, N. (2024). Crystal structure of p53 Y220C mutant in complex with PC-9859. Protein Data Bank: 9br4. |
CMCF-ID |
PDB Deposition |
Health |
| Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of LC3A in complex with the LIR of TP53INP2/DOR. Protein Data Bank: 8t4t. |
CMCF-ID |
PDB Deposition |
Health |
| Anderson, A.C.; Malloch, T.; Clarke, A.J. (2024). Crystal structure of the peptidoglycan O-acetyltransferase B (PatB) from Campylobacter jejuni, catalytic domain. Protein Data Bank: 8tlb. |
CMCF-ID |
PDB Deposition |
Health |
| Baird, J.; Holliday, M. (2024). Human Bcl-2 (G101V Mutant)/Bcl-xL Chimera Fused to Maltose-Binding Protein. Protein Data Bank: 8vwx. |
CMCF-ID |
PDB Deposition |
Health |