| Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Leontowich, Adam F. G.; Panahifar, Arash; Chen, Si; Barlow, Burke; Gurney, Kirsty E. B. et al. (2025). Lead micro- and nanoparticles directly observed within gunshot wounds in hunted game meat. Scientific Reports 15(1) . 10.1038/s41598-025-20285-2. |
BMIT-ID, EIML |
Peer-Reviewed Article |
Health |
| Mundboth, Kiran (2025). Canadian Light Source – 20 Years of Discovery. Canadian Journal of Chemistry . 10.1139/cjc-2024-0278. |
BMIT, BXDS, CMCF, FAR-IR, HXMA, MID-IR, SM |
Peer-Reviewed Article |
Health |
| Mundboth, Kiran (2025). Canadian Light Source – 20 Years of Discovery. Canadian Journal of Chemistry . 10.1139/cjc-2024-0278. |
BMIT, BXDS, CMCF, FAR-IR, HXMA, MID-IR, SM |
Peer-Reviewed Article |
Health |
| Liu, Yihong; McLeod, John A.; Chang, Lo-Yueh; Chang, Chung-Kai; Jiang, Yingying et al. (2024). The effect of annealing temperature on the site occupancy and the persistent luminescence of Mn2+-doped magnesium germanate. Materials Today Communications 38, 108080. 10.1016/j.mtcomm.2024.108080. |
HXMA, SGM |
Peer-Reviewed Article |
Health |
| Pushie, M Jake; Sylvain, Nicole J; Hou, Huishu; Pendleton, Nicole; Wang, Richard et al. (2024). X-ray fluorescence mapping of brain tissue reveals the profound extent of trace element dysregulation in stroke pathophysiology. Metallomics . 10.1093/mtomcs/mfae054. |
BIOXAS-IMAGING, IDEAS, MID-IR |
Peer-Reviewed Article |
Health |
| Black, Tallan; Boseley, Rhiannon E.; Quirk, Amanda; Young, Kaylen M.; Lunardi-Baccetto, Sarah et al. (2026). Adult Rat Offspring Exposed to THC during Gestation Exhibit Distinct Biomolecular Changes Identified by X-ray Fluorescence Imaging and Fourier Transform Infrared Spectroscopy in Cortico-Limbic Circuits. ACS Chemical Neuroscience . 10.1021/acschemneuro.5c00752. |
BIOXAS-IMAGING, MID-IR |
Peer-Reviewed Article |
Health |
| Mundboth, Kiran (2025). Canadian Light Source – 20 Years of Discovery. Canadian Journal of Chemistry . 10.1139/cjc-2024-0278. |
BMIT, BXDS, CMCF, FAR-IR, HXMA, MID-IR, SM |
Peer-Reviewed Article |
Health |
| Pushie, M Jake; Sylvain, Nicole J; Hou, Huishu; Pendleton, Nicole; Wang, Richard et al. (2024). X-ray fluorescence mapping of brain tissue reveals the profound extent of trace element dysregulation in stroke pathophysiology. Metallomics . 10.1093/mtomcs/mfae054. |
BIOXAS-IMAGING, IDEAS, MID-IR |
Peer-Reviewed Article |
Health |