Publication Beamlines Strategic Pillar
Poullennec, Karine G.; Jnoff, Eric; Abendroth, Jan; Bhuma, Naresh; Calmiano, Mark et al. (2024). Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies. Journal of Medicinal Chemistry 67(23) , 20879-20910. 10.1021/acs.jmedchem.4c01237. [PDB: 8uoj] CMCF-ID Health
Tian, Yuqing; Worrall, Liam J.; Sim, Lyann; Liu, Feng; Nasseri, Seyed A. et al. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis 14(17) , 13497-13508. 10.1021/acscatal.4c03643. [PDB: 9awt, 9ay8, 9ayu] CMCF-BM, CMCF-ID Health
Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] CMCF-BM Health
Alizadeh Sardroud, Hamed; Rosa, Gustavo Dos Santos; Dust, William; Cham, Tat-Chuan; Roy, Gwen et al. (2024). Comparison study on hyaline cartilage versus fibrocartilage formation in a pig model by using 3D-bioprinted hydrogel and hybrid constructs. Biofabrication 17(1) , 015014. 10.1088/1758-5090/ad88a6. BMIT-ID Health
Marcozzi, Tatiana; Baviriseaty, Sruthika; Yawman, Phillip; Zhang, Shawn; Vervaet, Chris et al. (2025). Synchrotron computed tomography combined with AI-based image analysis for the advanced characterization of spray dried amorphous solid dispersion particles. Journal of Pharmaceutical Sciences 114(1) , 530-543. 10.1016/j.xphs.2024.10.033. BMIT-BM Health
Zhou, Yuebiao; Aliagas, Ignacio; Wang, Shumei; Li, Chun Sing; Liu, Zhiguo et al. (2024). Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorganic and Medicinal Chemistry Letters , 130026. 10.1016/j.bmcl.2024.130026. [PDB: 9dc8, 9dc9] CMCF-BM Health
Bissegger, Lukas; Constantin, Theodora A.; Keles, Erhan; Raguž, Luka; Barlow-Busch, Isobel et al. (2024). Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling. Chemical Science . 10.1039/d4sc05459h. [PDB: 8twy] CMCF-ID Health
Pushie, M Jake; Sylvain, Nicole J; Hou, Huishu; Pendleton, Nicole; Wang, Richard et al. (2024). X-ray fluorescence mapping of brain tissue reveals the profound extent of trace element dysregulation in stroke pathophysiology. Metallomics . 10.1093/mtomcs/mfae054. BIOXAS-IMAGING, IDEAS, MID-IR Health
Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] CMCF-BM Health
Loundagin, Lindsay L.; Harrison, Kim D.; Wei, Xuan; Cooper, David M.L. (2024). Understanding basic multicellular unit activity in cortical bone through 3D morphological analysis: New methods to define zones of the remodeling space. Bone 179, 116960. 10.1016/j.bone.2023.116960. BMIT-ID Health
Brown, Alyssa; Zhu, MengYu; Rohani, Alireza; Ladak, Hanif; Agrawal, Sumit K. et al. (2024). Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy. Laryngoscope 134(6) , 2879-2888. 10.1002/lary.31259. BMIT-ID Health
Giese, Dina; Rask-Andersen, Helge; Ladak, Hanif M.; Agrawal, Sumit; Li, Hao et al. (2024). Synchrotron Phase-Contrast Imaging and Cochlear Otosclerosis: A Case Report. Audiology and Neurotology 29(6) , 487–499. 10.1159/000539422. BMIT-ID Health
Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] CMCF-ID Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health