| Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] |
CMCF-BM |
Peer-Reviewed Article |
Materials |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39Q mutant. Protein Data Bank: 9dfq. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K23/24Q mutant. Protein Data Bank: 9dfp. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K31Q mutant. Protein Data Bank: 9dfo. |
CMCF-BM |
PDB Deposition |
Health |
| Grainger, R.; Colussi, D.C.; Noble, M.; Junop, M.; Stathopulos, P.B. et al. (2025). Human mitochondrial calcium uniporter crystal structure (residues 74-165 resolved) with lithium. Protein Data Bank: 8urg. |
CMCF-BM |
PDB Deposition |
Health |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 13). Protein Data Bank: 8t5r. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor compound 5. Protein Data Bank: 9dc9. |
CMCF-BM |
PDB Deposition |
Health |
| Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor G1. Protein Data Bank: 9dc8. |
CMCF-BM |
PDB Deposition |
Health |
| Hedges, Jason (2024). Biochemical and structural studies of enzymes from the azomycin and beta-ethynylserine biosynthetic pathways. Supervisor: Ryan, Katherine S.. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/79048. |
CMCF-BM, CMCF-ID |
Doctoral Thesis |
Health |
| Hemmings, M.; Zielinski, M.; Blanchet, J.; Golkar, T.; Berghuis, A.M. et al. (2025). Structure of aminoglycoside acetyltransferase AAC(3)-Ia in complex with sisomicin and CoA. Protein Data Bank: 9mgs. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Holyoak, T.; Tran, N. (2025). Staphylococcus aureus exfoliative toxin A D164E variant. Protein Data Bank: 9bsm. |
CMCF-BM |
PDB Deposition |
Health |
| Holyoak, T.; Tran, N. (2025). Staphylococcus aureus exfoliative toxin A D164A variant. Protein Data Bank: 9bsh. |
CMCF-BM |
PDB Deposition |
Health |