| Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of
S. aureus
TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science Advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Cho, Timothy HS (2024). Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli. Supervisor: Raivio, Tracy. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-kpc4-mn64. |
CMCF-BM |
Doctoral Thesis |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39Q mutant. Protein Data Bank: 9dfq. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K23/24Q mutant. Protein Data Bank: 9dfp. |
CMCF-BM |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K31Q mutant. Protein Data Bank: 9dfo. |
CMCF-BM |
PDB Deposition |
Health |
| Whittington, D.A. (2025). Crystal structure of truncated USP1:UAF1 in complex with compound 18. Protein Data Bank: 9n9y. |
CMCF-BM |
PDB Deposition |
Health |
| Holyoak, T.; Tran, N. (2025). Staphylococcus aureus exfoliative toxin A D164E variant. Protein Data Bank: 9bsm. |
CMCF-BM |
PDB Deposition |
Health |