| Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Veyron, S.; Cummer, R. (2024). C. difficile Tcdb cysteine protease domain in complex with IP6. Protein Data Bank: 9bja. |
CMCF-ID |
PDB Deposition |
Health |
| Vu, Binh T.; Dominique, Romyr; Fahr, Bruce J.; Li, Hongju H.; Fry, David C. et al. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.4c00379. [PDB: 9br4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP2. Protein Data Bank: 9cs1. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP1. Protein Data Bank: 9cs0. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wallweber, H.; Hsu, P.L. (2024). Crystal structure of Para.09 bound to TREM2. Protein Data Bank: 8t59. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Cheng, W.; Lv, Z.; Guo, S.; Lin, D. et al. (2023). The Crystal Structure of PPARg from Biortus.. Protein Data Bank: 8wfe. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Ni, C. et al. (2023). The Crystal Structure of PAK1 kinase domain from Biortus.. Protein Data Bank: 8x5z. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Ni, C. et al. (2023). The Crystal Structure of PKCi from Biortus. Protein Data Bank: 8wzd. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Ni, C. et al. (2024). The Crystal Structure of ClpC1-NTD from Biortus.. Protein Data Bank: 8xqu. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Ni, C. et al. (2024). The Crystal Structure of Apaf from Biortus.. Protein Data Bank: 8xqk. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Ni, C. et al. (2024). The Crystal Structure of PTPRG from Biortus.. Protein Data Bank: 8xqd. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2024). Structure of the PGK1 from Biortus.. Protein Data Bank: 8yhp. |
CMCF-ID |
PDB Deposition |
Health |