| Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Saran, A.; Zeytuni, N. (2024). PorX phosphatase null mutant (T271V). Protein Data Bank: 8thp. |
CMCF-ID |
PDB Deposition |
Health |
| Saran, A.; Zeytuni, N. (2024). PorX with Zn (primitive orthorhombic crystal form). Protein Data Bank: 8tfm. |
CMCF-ID |
PDB Deposition |
Health |
| Xu, J.; Fu, Y.; Ding, X.; Meng, Q.; Wang, L. et al. (2024). co-crystal structure of non-carboxylic acid inhibitor with PHD2. Protein Data Bank: 8j1k. |
CMCF-ID |
PDB Deposition |
Health |
| Kozlov, G.; Jiang, J.; Gehring, K. (2024). LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA. Protein Data Bank: 8g91. |
CMCF-ID |
PDB Deposition |
Health |
| Kozlov, G.; Jiang, J.; Gehring, K. (2024). LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA. Protein Data Bank: 8g90. |
CMCF-ID |
PDB Deposition |
Health |
| Ghosh, K. (2024). Human CK1 Delta Kinase structure bound to Inhibitor. Protein Data Bank: 8izc. |
CMCF-ID |
PDB Deposition |
Health |
| Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of
S. aureus
TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science Advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gunn, R.J.; Lawson, J.D. (2024). PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).. Protein Data Bank: 8v8h. |
CMCF-ID |
PDB Deposition |
Health |
| Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hughes, M.P.; Taylor, J.P. (2024). Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide. Protein Data Bank: 8th7. |
CMCF-ID |
PDB Deposition |
Health |
| Yang, Zemin; Johnson, Bryan A.; Meliopoulos, Victoria A.; Ju, Xiaohui; Zhang, Peipei et al. (2023). Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication. npj Computational Materials . 10.1101/2023.06.29.546885. [PDB: 8th7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Brooks, C.L.; Aguilar, E.N. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkl. |
CMCF-ID |
PDB Deposition |
Health |
| Brooks, C.L.; Murray, B. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkk. |
CMCF-ID |
PDB Deposition |
Health |