Publication Beamlines Strategic Pillar
Merchant, Rohan R.; Chernyak, Natalia; Lopez, Jovan A.; Sharp, Phillip P.; Mandal, Mihir et al. (2026). N -Alkyl and N -Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors. ACS Medicinal Chemistry Letters 17(3) , 744-749. 10.1021/acsmedchemlett.6c00066. [PDB: 10qs] CMCF-BM Agriculture
Merchant, R.R.; Chernyak, N.; Lopez, J.A.; Sharp, P.P.; Mandal, M. et al. (2026). N-Alkyl & N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 13 ((3'R)-1'-{5-amino-1-[(2S)-1,1,1-trifluorobutan-2-yl]-1H-pyrazole-4-carbonyl}-6-chloro-5-fluorospiro[[3,1]benzoxazine-4,3'-piperidin]-2(1H)-one). Protein Data Bank: 10qs. CMCF-BM Materials
Mosimann, W.A.; Strynadka, N.C.J.; Worrall, L.J. (2026). Staphylococcus aureus serine/threonine kinase Stk1 with inhibitor GW779439X. Protein Data Bank: 9ymt. CMCF-BM Agriculture
Mrozek, A.; Chen, Y.; Antoshchenko, T.; Park, H.W. (2023). Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 8-Aminoadenosine. Protein Data Bank: 8d1q. CMCF-BM Agriculture
Mrozek, A.; Park, H.W. (2023). Crystal structure of Plasmodium falciparum GRP78-NBD in complex with Piclidenoson. Protein Data Bank: 8d22. CMCF-BM Agriculture
Mrozek, A.; Park, H.W. (2023). Crystal structure of Plasmodium falciparum GRP78 in complex with 5'-Methylthioadenosine. Protein Data Bank: 8d20. CMCF-BM Agriculture
Mrozek, A.; Park, H.W. (2023). Crystal structure of Plasmodium falciparum GRP78 in complex with Trans-Zeatin Riboside. Protein Data Bank: 8d1y. CMCF-BM Agriculture
Muna, Tasneem Hassan; Rutbeek, Nicole R; Horne, Julia; Lao, Ying W; Krokhin, Oleg V et al. (2024). The phage protein paratox is a multifunctional metabolic regulator of Streptococcus. Nucleic Acids Research . 10.1093/nar/gkae1200. [PDB: 8vsq] CMCF-BM Health
Musil, D.; Toure, M. (2023). CRYSTAL STRUCTURE OF HUMAN HPK1 (MAP4K1) COMPLEX WITH 2-[8-Amino-7-fluoro-6-(8-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-yl)-isoquinolin-3-ylamino]-6-isopropyl-5,6-dihydro-4H-1,6,8a-triaza-azulen-7-one. Protein Data Bank: 8cij. CMCF-BM Agriculture
Nasseri, Seyed Amirhossein; Lazarski, Aleksander C.; Lemmer, Imke L.; Zhang, Chloe Y.; Brencher, Eva et al. (2024). An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature . 10.1038/s41586-024-07574-y. [PDB: 8tdi] CMCF-BM Health
Niu, Xun (2024). Valorization of wood bark towards value-added chemicals, structures, and bioproducts. Supervisor: Rojas, Orlando J.. British Columbia, Canada: University of British Columbia. https://open.library.ubc.ca/soa/cIRcle/collections/ubctheses/24/items/1.0445091?o=14. CMCF-BM Materials
Palte, R.L.; Eddins, M.; Vara, B.A.; Schneider, S.E. (2026). Crystal structure of TEAD2 with non-covalent aryl ether inhibitor.. Protein Data Bank: 9yk2. CMCF-BM Health
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health
Penner, T.V.; Prehna, G. (2024). Crystal structure of Sel-1 repeat protein LceB from Legionella pneumophila. Protein Data Bank: 8sxq. CMCF-BM Agriculture
Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. [PDB: 8cyu, 8cyz, 8sxr] CMCF-BM Health