Publication Beamlines Strategic Pillar
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1225. Protein Data Bank: 5sd0. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1224. Protein Data Bank: 5scz. CMCF-ID Health
Serrano-Negron, J.E.; King, D.T.; Vocadlo, D.J. (2022). Homocitrullinated beta-lactamase OXA-48. Protein Data Bank: 7lxg. CMCF, CMCF-ID Health
Sharon, I.; Schmeing, T.M. (2022). Crystal structure of cyanophycin synthetase 2 from Gloeothece citriformis. Protein Data Bank: 7ta5. CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochimica et Biophysica Acta - General Subjects 1866(11) , 130217. 10.1016/j.bbagen.2022.130217. [PDB: 7uqv] CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Sharon, Itai; McKay, Geoffrey A.; Nguyen, Dao; Schmeing, T. Martin (2023). Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proceedings of the National Academy of Sciences of the United States of America 120(8) . 10.1073/pnas.2216547120. CMCF-BM Health
Sharon, Itai; Schmeing, T. Martin (2023). Bioinformatics of cyanophycin metabolism genes and characterization of promiscuous isoaspartyl dipeptidases that catalyze the final step of cyanophycin degradation. Scientific Reports 13(1) . 10.1038/s41598-023-34587-w. CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Shen, Y.; Guarne, A. (2022). Crystal structure of TnsC(1-503)A225V. Protein Data Bank: 7mbw. CMCF-BM Health
Shen, Yi; Wen, Yurong; Sposini, Silvia; Vishwanath, Anjali Amrapali; Abdelfattah, Ahmed S. et al. (2023). Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sensors . 10.1021/acssensors.3c00484. [PDB: 7yv3, 7yv5] CMCF-ID Health
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] CMCF-BM Health
Sietsema, D.V. (2025). Crystal Structure of human cyclic GMP-AMP synthase (cGAS) in complex with compound 36; (S)-(6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(5-(2-hydroxyethoxy)pyrimidin-2-yl)methanone. Protein Data Bank: 9mdc. CMCF-ID Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100016. Protein Data Bank: 9cux. CMCF-BM Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100013. Protein Data Bank: 9cuw. CMCF-BM Health