Publication Beamlines Strategic Pillar
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] CMCF-BM Health
Li, Kunhua; Tokareva, Olena S.; Thomson, Ty M.; Wahl, Sebastian C. T.; Travaline, Tara L. et al. (2022). De novo mapping of α-helix recognition sites on protein surfaces using unbiased libraries. Proceedings of the National Academy of Sciences of the United States of America 119(52) . 10.1073/pnas.2210435119. [PDB: 7uwi] CMCF-ID Health
Li, Hao; Agrawal, Sumit; Zhu, Ning; Cacciabue, Daniela I.; Rivolta, Marcelo N. et al. (2024). A novel therapeutic pathway to the human cochlear nerve. Scientific Reports 14(1) , 26795. 10.1038/s41598-024-74661-5. BMIT-ID Health
Li, Hao; Agrawal, Sumit; Rohani, Seyed Alireza; Zhu, Ning; Cacciabue, Daniela I. et al. (2022). Unlocking the human inner ear for therapeutic intervention. Scientific Reports 12, 18508. 10.1038/s41598-022-22203-2. BMIT-ID Health
Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science Advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] CMCF-ID Health
Lewis, H.A.; Muckelbauer, J.K. (2022). CRYSTAL STRUCTURE OF HIV-1 INTEGRASE COMPLEXED WITH (2S)-2-(TERT-BUTOXY)-2-(5-{2-[(2-CHLORO-6-M ETHYLPHENYL)METHYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL}-4- (4,4-DIMETHYLPIPERIDIN-1-YL)-2-METHYLPYRIDIN-3-YL)ACETIC ACID. Protein Data Bank: 7uoq. CMCF-ID Health
Leontowich, Adam F. G.; Panahifar, Arash; Ostrowski, Ryan (2022). Fragmentation of hunting bullets observed with synchrotron radiation: Lighting up the source of a lesser-known lead exposure pathway. PLoS ONE 17(8) , e0271987. 10.1371/journal.pone.0271987. BMIT-ID, IDEAS Health
Leontowich, Adam F. G.; Panahifar, Arash; Ostrowski, Ryan (2022). Fragmentation of hunting bullets observed with synchrotron radiation: Lighting up the source of a lesser-known lead exposure pathway. PLoS ONE 17(8) , e0271987. 10.1371/journal.pone.0271987. BMIT-ID, IDEAS Health
Lee, J.; Miranda-Zaragoza, B.; Rodriguez-Almazan, C.; Strynadka, N.C.J. (2025). Thermus thermophilus HB27 laccase (Tth-Lac) mutant with partial deletion of beta-hairpin sequence. Protein Data Bank: 9cpm. CMCF-ID Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence. Protein Data Bank: 8ds1. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2). Protein Data Bank: 8drx. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence. Protein Data Bank: 8dru. CMCF-BM Health
Lee, Jaeyong; Kenward, Calem; Worrall, Liam J.; Vuckovic, Marija; Gentile, Francesco et al. (2022). X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nature Communications 13(1) . 10.1038/s41467-022-32854-4. [PDB: 8dru, 8drx, 8ds1] CMCF-BM Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] CMCF-BM Health
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2. Protein Data Bank: 8v31. CMCF-BM Health