Publication Beamlines Strategic Pillar
Fakih, Rayan; Sauvé, Véronique; Gehring, Kalle (2022). Structure of the second phosphoubiquitin–binding site in parkin. Journal of Biological Chemistry 298(7) , 102114. 10.1016/j.jbc.2022.102114. [PDB: 7us1] CMCF-BM Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] CMCF-BM Health
Navas, Laura E.; Zahn, Michael; Bajwa, Harbir; Grigg, Jason C.; Wolf, Megan E. et al. (2022). Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. Journal of Biological Chemistry 298(5) , 101871. 10.1016/j.jbc.2022.101871. [PDB: 7q2a] CMCF-BM Health
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] CMCF-BM Health
Vergunst, Kathleen L.; Langelaan, David N. (2022). The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation. Scientific Reports 12(1) . 10.1038/s41598-021-04223-6. CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Stille, Julia K.; Tjutrins, Jevgenijs; Wang, Guanyu; Venegas, Felipe A.; Hennecker, Christopher et al. (2022). Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors. European Journal of Medicinal Chemistry 229, 114046. 10.1016/j.ejmech.2021.114046. [PDB: 7mlf] CMCF-BM Health
Ivanochko, Danton; Miura, Kazutoyo; Hailemariam, Sophia; Ravichandran, Rashmi; Song, Yiting et al. (2026). A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity. Nature Communications . 10.1038/s41467-026-68761-1. CMCF-ID Health
Haines, Eric; Burke, Michael; Catterall, Rachel; De Jesus, Victor; Hidalgo, Daniel et al. (2026). The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers. Nature Cancer . 10.1038/s43018-025-01081-3. [PDB: 9ecu] CMCF-ID Health
Kwon, Min Chul; Thuring, Jan Willem; Querolle, Olivier; Dai, Xuedong; Verhulst, Tinne et al. (2024). Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias. Blood 144(11) , 1206-1220. 10.1182/blood.2023022480. [PDB: 9z4x] CMCF-ID Health
Kimani, Serah W.; Noureldin, Mahmoud; Wilson, Brian; Hoffer, Laurent; Green, Stuart R. et al. (2025). OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Communications Biology 8(1) . 10.1038/s42003-025-08491-0. [PDB: 9yv4] CMCF-ID Health
Wang, Mingyu; Du, Grace; Yongo‐Luwawa, Charity; Lu, Angelina; Kinrade, Brett et al. (2025). Peptide‐based ligand antagonists block a Vibrio cholerae adhesin. FEBS Letters . 10.1002/1873-3468.70231. [PDB: 9y9w, 9ybq] CMCF-ID Health
Luo, Chuanyun; Paetzel, Mark (2025). Crystal structure of Escherichia coli type I signal peptidase P84A in complex with lipopeptide antibiotic arylomycin A2. Journal of Structural Biology 217(4) , 108260. 10.1016/j.jsb.2025.108260. [PDB: 9nlo] CMCF-ID Health
Ereño-Orbea, June; Pang, Lijuan; Sicard, Taylor; Nycholat, Corwin; Cui, Hong et al. (2025). Molecular Insights into the Engagement of High-Affinity Sialylated Ligands to Human CD22. JACS Au . 10.1021/jacsau.5c01013. [PDB: 9rm3, 9ro7, 9rob] CMCF-BM, CMCF-ID Health