Publication Beamlines Strategic Pillar
Uguen, Mélanie; Shell, Devan J.; Silva, Madhushika; Deng, Yu; Li, Fengling et al. (2025). Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells. Nature Communications 16(1) . 10.1038/s41467-025-57005-3. [PDB: 9cuw, 9cux] CMCF-BM Health
Van Schepdael, Matthew; Asakereh, Iman; Colautti, Jake; Gierys, Andrew J.; Sachar, Kartik et al. (2026). Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release. Nature Communications . 10.1038/s41467-025-68138-w. [PDB: 9mvg] CMCF-BM Health
Vara, Brandon A.; Lim, Jongwon; Moure, Casey J.; Schneider, Sebastian E.; Yeung, Charles S. et al. (2026). Discovery and In Vivo Evaluation of Aryl Ether YAP1/TEAD Inhibitors for the Treatment of Hippo-Driven Malignancies. Journal of Medicinal Chemistry 69(4) , 4303-4316. 10.1021/acs.jmedchem.5c02997. [PDB: 9yk2] CMCF-BM Health
Vergunst, Kathleen L.; Langelaan, David N. (2022). The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation. Scientific Reports 12(1) . 10.1038/s41598-021-04223-6. CMCF-BM Health
Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. CMCF-BM, CMCF-ID Health
Zhou, Yuebiao; Aliagas, Ignacio; Wang, Shumei; Li, Chun Sing; Liu, Zhiguo et al. (2024). Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorganic and Medicinal Chemistry Letters , 130026. 10.1016/j.bmcl.2024.130026. [PDB: 9dc8, 9dc9] CMCF-BM Health
Niu, Xun (2024). Valorization of wood bark towards value-added chemicals, structures, and bioproducts. Supervisor: Rojas, Orlando J.. British Columbia, Canada: University of British Columbia. https://open.library.ubc.ca/soa/cIRcle/collections/ubctheses/24/items/1.0445091?o=14. CMCF-BM Materials
Merchant, R.R.; Chernyak, N.; Lopez, J.A.; Sharp, P.P.; Mandal, M. et al. (2026). N-Alkyl & N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 13 ((3'R)-1'-{5-amino-1-[(2S)-1,1,1-trifluorobutan-2-yl]-1H-pyrazole-4-carbonyl}-6-chloro-5-fluorospiro[[3,1]benzoxazine-4,3'-piperidin]-2(1H)-one). Protein Data Bank: 10qs. CMCF-BM Materials
Fedoretz-Maxwell, Brooklyn (2022). Investigations of secondary coordination sphere interactions involving aromatic amino acid residues in metalloproteins. Supervisor: Warren, Jeffrey J.;. British Columbia, Canada: Simon Fraser University. https://summit.sfu.ca/item/35856. CMCF-BM Materials
Beh, Daniel W.; Cuellar De Lucio, Alejandro J.; del Rosal, Iker; Maron, Laurent; Spasyuk, Denis et al. (2023). Organotitanium Complexes Supported by a Dianionic Pentadentate Ligand. Organometallics 42(11) , 1149-1157. 10.1021/acs.organomet.2c00609. CMCF-BM Materials
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Materials
Huynh, Racheal P. S.; Evans, David R.; Lian, Jian Xiang; Spasyuk, Denis; Siahrostrami, Samira et al. (2023). Creating Order in Ultrastable Phosphonate Metal–Organic Frameworks via Isolable Hydrogen-Bonded Intermediates. Journal of the American Chemical Society 145(39) , 21263-21272. 10.1021/jacs.3c05279. CMCF-BM Materials
Lin, Lirong; Tresp, David S.; Spasyuk, Denis M.; Lalancette, Roger A.; Prokopchuk, Demyan E. et al. (2024). Accessing Ni(0) to Ni(IV) via nickel–carbon–phosphorus bond reorganization. Chemical Communications 60(6) , 674-677. 10.1039/d3cc04687g. CMCF-BM Materials
Niu, Xun; Foster, E. Johan; Patrick, Brian O.; Rojas, Orlando J. (2022). Betulin Self‐Assembly: From High Axial Aspect Crystals to Hedgehog Suprastructures. Advanced Functional Materials 32(44) , 2206058. 10.1002/adfm.202206058. CMCF-BM Materials
Scanda, Karla; Avila, Yosuan; Sánchez, Laritza; Mojica Molina, Hebert Rodrigo; González, Marlene M. et al. (2023). Thermally-induced spin-crossover (SCO) in Fe(4-Ethynylpyrdine)2[Fe(CN)5NO]. Why is the SCO observed in 2D ferrous nitroprussides despite the NO-NC repulsive interaction in the interlayer region?. New Journal of Chemistry . 10.1039/d3nj04638a. CMCF-BM Materials