| Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence. Protein Data Bank: 8dru. |
CMCF-BM |
PDB Deposition |
Health |
| Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lorente Cobo, Neil; Sibinelli-Sousa, Stephanie; Biboy, Jacob; Vollmer, Waldemar; Bayer-Santos, Ethel et al. (2022). Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold. Journal of Biological Chemistry 298(11) , 102556. 10.1016/j.jbc.2022.102556. [PDB: 7uo3, 7uo8] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Mabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Leung, Elisa; Chuang, Stephanie H.W. et al. (2022). Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure . 10.1016/j.str.2022.12.002. [PDB: 7uvm, 7uvn, 7uvr, 7uvu, 7uw0] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szn. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szm. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2023). Crystal structure of human ClpP protease in complex with TR-133. Protein Data Bank: 7uw0. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2023). Crystal structure of human ClpP protease in complex with TR-107. Protein Data Bank: 7uvu. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2023). Crystal structure of human ClpP protease in complex with TR-65. Protein Data Bank: 7uvr. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2023). Crystal structure of human ClpP protease in complex with TR-57. Protein Data Bank: 7uvn. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2023). Crystal structure of human ClpP protease in complex with TR-27. Protein Data Bank: 7uvm. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Wilson, B.J.; Alvarez, H.G.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40333. Protein Data Bank: 9b9h. |
CMCF-BM |
PDB Deposition |
Health |